CHRONIC MYELOPROLIFERATIVE DISORDERS

Question 1

⦿ Characterized by hypercellular marrow, erythrocytosis, granulocytosis, and thrombocytosis, Myelofibrosis
⦿ Defect of the myeloid stem cell. Increased production, growth, and proliferation

A. CHRONIC MYELOPROLIFERATIVE DISORDERS
B. Polycythemia Vera
C. ACUTE MYELOPROLIFERATIVE DISORDERS

Answer 1

A. CHRONIC MYELOPROLIFERATIVE DISORDERS

Question 2

⦿ Named for the cell line most greatly affected
⦿ All may terminate or lead to acute leukemia

A. CHRONIC MYELOPROLIFERATIVE

B. CHRONIC MYELOGENOUS LEUKEMIA

Answer 2

A. CHRONIC MYELOPROLIFERATIVE DISORDERS

Question 3

⦿ Named for the cell line most greatly affected

⦿ All may terminate or lead to acute leukemia

A. CHRONIC MYELOPROLIFERATIVE

B. CHRONIC MYELOGENOUS LEUKEMIA

Answer 3

A. CHRONIC MYELOPROLIFERATIVE

Question 4

- ONCOGENE GENE USED FOR: Polycythemia vera (rbc, granulocyte,platelets), Chronic idiopathic myelofibrosis, Essential
thrombocythemia

A.- JAK2 oncogene
B.- BCR/ABL oncogene

Answer 4

A.- JAK2 oncogene

Question 5

Chronic Myelogenous Leukemia/ ALL/AML – Philadelphia chromosome

A.- JAK2 oncogene
B.- BCR/ABL oncogene

Answer 5

B.- BCR/ABL oncogene

Question 6

recorded when there is an increase in hematopoietic cells relative to adipocytes compared with concurrent controls.

A. Polycythemia Vera
B. Chronic Myelogenous Leukemia (CML)
C.Hypercellular Marrow

Answer 6

C.Hypercellular Marrow