Chronic lymphoblastic leukaemia Flashcards

1
Q

Who gets CLL and what symptoms?

A

Mainly elderly patients picked up of FBC.
Most common leukaemia in adults.
Can cause lymphadenopathy and B symptoms.

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2
Q

CLL- blood results?

A

Anaemia, lymphocytosis.

Polyclonal accumulation of mature lymphocytes, B cells, that are fragile and burst on blood film -> smear cells.

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3
Q

CLL- treatment?

A

Majority never progress and don’t need treatment.

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4
Q

CLL- complications?

A

Anaemia, recurrent infections, warm haemolytic anaemia, transform into high grade non-Hodgkin’s lymphoma via…

Ritcher’s transformation- lymph node swelling, fever without infection, weight loss, night sweats, nausea, abdominal pain.

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