Chronic Kidney Disease Flashcards
1
Q
what is the definition of chronic kidney disease
A
reduction in kidney function or structural damage or both present for over 3 months with associated health implications
2
Q
who should CKD be diagnosed in
A
people with markers of kidney damage -Transplant history -Histological abnormalities on biopsy -Electrolyte abnormalities due to tubular disorders -ACR>3mg/mmol -Sediment in urine -Structural abnormalities on imaging and or persistent reduction in renal function shown by. eGFR of less than 60mL/min/1.73m2
3
Q
what is an ‘accelerated progression’ of CKD
A
- persistent decrease in eGFR of 25% or more and a change in CKD category within 12 months
- persistent decrease in eGFR of 15ml/min/1.73m2 within 12 months
4
Q
what is the most common cause of CKD
A
diabetes
5
Q
what are some nephrotoxic drugs
A
aminoglycosides, ACE inhibitors, ARB’s, bisphosphonates, NSAID’s
