Chromosomes Flashcards
1
Q
What are the classes of chromosomes?
A
2
Q
What are the characteristics of gimsa staining?
A
3
Q
High resolution banding
A
· Increases resulution by arresting chromosomes in pro-meta phase when the chromatin is less dense allowing for greater resolution
- gimsa or R-banding staining protocol
4
Q
What are the 4 chromosomes that can be trisomy?
A
Trisomy 13 (Patau syndrome) – frequency 1/22,700 live births
Trisomy 18 (Edward syndrome) – frequency 1/7,500 live births
Trisomy 21 (Down syndrome) – frequency 1/580 live births
Trisomy X (47,XXX) – frequency 1/900 newborn females
5
Q
What is the one viable monosomy?
A
Turner’s syndrome
Turner syndrome, monosomy X (45,X) – frequency 1/4000 newborn females
