Chromosomal Genetics + Eugenics Revision Flashcards
1
Q
Mitosis consists of five phases:
A
- Prophase
- Interphase
- Metaphase
- Anaphase
- Telophase
2
Q
Be able to compare Mitosis and Meiosis I
A
- Make table m8
3
Q
The Evolutionary Enigma of Sexual Reproduction…
A
- We need variation
- n = ?
- Meiosis = lots of diff cells
4
Q
Why have sex?
A
- Changing environment
- Spatially variable environment
- Competition (better use of resources)
5
Q
Karyotype terminology…
A
- Chromosomal abnormalities, down syndrome…etc.
- Non disjunction
6
Q
95% of Down Syndrome babies have…
A
- Two maternal chromosome 21
7
Q
Diseases:
A
- Klinefelter
- Turner Syndrome XO
- Barr Body- Lyon Hypothesis
- Willems beuren syndrome
8
Q
Results of meiosis in a human inversion heterozygote
A
…
9
Q
Feeblemindedness model:
A
- nn = feeblemindedness
10
Q
Hardy Weinberg equations…
A
- Frequency of N = p
- Frequency of n = q ( 1 - p )
- Nn = 2pq
- nn = 2pq^2 ?
11
Q
Eugenics…
A
- Some data was shonky
- Today we value individual rights more
- Medical rights
- Privacy
12
Q
The closer they are..
A
- The less recombination there is
13
Q
Genotypic Frequency = ?
A
- 1 in 2500 children are born with cystic fibrosis. What proportion of the population are carriers for disease?
- 1/2500 = q^2
- q = 1/50 / 0.02
- p + q = 1
- p = 0.98
- 2pq = 2(0.98 x 0.02) = 0.0392
14
Q
Pleiotropy =
A
- One gene controls a lot of things
15
Q
Epistasis =
A
- Two or more genes interact in some way
