Chromoblastomycosis Flashcards
1
Q
What is the genus of 3 common species that cause chromoblastomycosis?
A
- Fonsecaea
- Phialophora
- Cladophialophora
2
Q
What is the geographic distribution of fungi that cause chromoblastomycosis?
A
Found worldwide but most common in tropical and subtropical areas
3
Q
How is infection with fungi causing chromoblastomycosis acquired?
A
Traumatic percutaneous inoculation (e.g. contaminated sliver of wood)
4
Q
What are clinical features of chromoblastomycosis?
A
Chromoblastomycosis
* Painless chronic skin lesions develop over years
* Veruccous nodules or cauliflower-like masses
* Gradually spread centripetally by cutaneous or lymphatic dissemination
* Male agricultural workers are most commonly affected
* Usually on legs
5
Q
How is chromoblastomycosis diagnosed?
A
- Microscopic examination of skin scrapings or biopsies showing characteristic cells
- Rounded, thick-walled, chestnut brown fungal cells (often in a wall-like pattern) on wet film
- Branching hyphae on KOH prep
- Confirmed through cultures that take longer
6
Q
What is the treatment for chromoblastomycosis?
A
- Itraconazole, OR
- Terbinafine
