Christie Flashcards

1
Q

what percentage of the islet cell volume do B-cells occupy?

A

25%

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2
Q

B-cells

A

Glucose uptake into cells are facilitated by GLUT-2

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3
Q

Not an action of insulin

A

decreases protein synthesis in muscle

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4
Q

Blood relatives

A

Insulitis

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5
Q

57 year old man

A

Loss of islet Beta Cells

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6
Q

Not an effect of incretins

A

Increase in appetite

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7
Q

Which pancreatic islet cells release glucagon?

A

Alpha

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8
Q

Insulin-dependent glucose uptake by skeletal muscle and adipocytes?

A

GLUT-4

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9
Q

Diabetic Hypoglycemia

A
  • occur in Type 1 or Type 2 diabetes mellitusn
  • due to insulin or oral hypoglycemic agents
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10
Q

Type II diabetes mellitus etiology

A

Metabolic

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11
Q

First choice of therapy for newly diagnosed Type II diabetic?

A

Diet therapy

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12
Q

Glucagon-like Peptide-1 is released from

A

small intestine

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13
Q

18 y.o

A
  • Elevated:
    • Glucose
    • Free Fatty Acids
    • Acetoacetic acid
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14
Q

Absent in MEN 1

A

thyroid Medullary Carcinoma

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15
Q

Which of the followingzones of the ovary contain the follicles?

A
  • Cortex
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16
Q

At what follicular stage is the egg release?

A

Graafian Follicle

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17
Q

During what phase of the menstrual cycle does estradiol have a positive feed back on GnRH?

A

Mid-cycle

18
Q

False about menopause

A
  • Progesterone deficiency is associated with most of its signs and symptoms
19
Q

False about follicular stage of menstraul cycle

A
  • responsible for secretory phase of the endometrium
20
Q

Non-reproductive effect of estradiol

A

Catabolic effect on bone

21
Q

Not an action of progesterone

A
  • During pregnancy, decreases uterine threshold to contractile stimuli
22
Q

Source of increase in concentration at point D is?

A

corpus luteum

23
Q

Wife of a friend

A

Endometriosis

24
Q

False about Endometriosis

A

Distant sites are never involve

ex: heart and lungs

25
Q

False about morning sickness

A
  • Never severe enough to require hospitalization
26
Q

What can be seen if there is disruption of pituitary stalk?

A
  • All of the above
    • Increase in prolactin levels
    • Decrease in:
      • FSH secretion
      • ACTH secretion
    • Drop in LH levels
27
Q

Flase about human placental lactogen

A

Protects against fetal hyperglycemia

28
Q

False about labor?

A
  • Well defined mechanism of delivary
29
Q

What is Responsible for estriol production during the second and third trimesters of pregnancy?

A
  • Placenta
  • Fetal Liver
  • Fetal Adrenal Gland
30
Q

Most common cause of abnormal uterine bleeding

A

Dysfunctional uterine bleeding

31
Q

Main cause of dysfunctional uterine bleeding?

A

anovulatory cycle (Failure to ovulate)

32
Q

T or F: Adolescent girls generally start their growth spurt later than do adolescent boys.

A

False

33
Q

What causes premenstrual syndrome?

A

decreased progesterone just before menses

34
Q

hCG

A

Uncertain Physiologic role after 9 weeks gestation

35
Q

Function of syncytiotrophoblast

A
  • Produces human chorionic gonadotropin
  • Adhesion
  • Invasion
  • Phagocytosis
36
Q

What is only secreted after implantation?

A

HCG

37
Q

Most responsible for increased uttering contractibility near term in pregnany

A
  • progesterone:estrogen ratio
38
Q

Main source of estrogen and progesterone after 8 weeks of pregnancy:

A

Placenta

39
Q

Which pituitary cell type is known to increase from 20% to 50% of pituitary volume during pregnancy?

A

Lactotroph

40
Q

Blood levels of which substance are described by curve B?

A

Progesterone

41
Q

What condition?

A

Abruptio Placenta

42
Q

The tissue shown in this illustration is which one of the following

A

proliferative endometrium