Christie Flashcards

1
Q

what percentage of the islet cell volume do B-cells occupy?

A

25%

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2
Q

B-cells

A

Glucose uptake into cells are facilitated by GLUT-2

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3
Q

Not an action of insulin

A

decreases protein synthesis in muscle

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4
Q

Blood relatives

A

Insulitis

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5
Q

57 year old man

A

Loss of islet Beta Cells

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6
Q

Not an effect of incretins

A

Increase in appetite

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7
Q

Which pancreatic islet cells release glucagon?

A

Alpha

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8
Q

Insulin-dependent glucose uptake by skeletal muscle and adipocytes?

A

GLUT-4

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9
Q

Diabetic Hypoglycemia

A
  • occur in Type 1 or Type 2 diabetes mellitusn
  • due to insulin or oral hypoglycemic agents
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10
Q

Type II diabetes mellitus etiology

A

Metabolic

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11
Q

First choice of therapy for newly diagnosed Type II diabetic?

A

Diet therapy

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12
Q

Glucagon-like Peptide-1 is released from

A

small intestine

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13
Q

18 y.o

A
  • Elevated:
    • Glucose
    • Free Fatty Acids
    • Acetoacetic acid
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14
Q

Absent in MEN 1

A

thyroid Medullary Carcinoma

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15
Q

Which of the followingzones of the ovary contain the follicles?

A
  • Cortex
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16
Q

At what follicular stage is the egg release?

A

Graafian Follicle

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17
Q

During what phase of the menstrual cycle does estradiol have a positive feed back on GnRH?

18
Q

False about menopause

A
  • Progesterone deficiency is associated with most of its signs and symptoms
19
Q

False about follicular stage of menstraul cycle

A
  • responsible for secretory phase of the endometrium
20
Q

Non-reproductive effect of estradiol

A

Catabolic effect on bone

21
Q

Not an action of progesterone

A
  • During pregnancy, decreases uterine threshold to contractile stimuli
22
Q

Source of increase in concentration at point D is?

A

corpus luteum

23
Q

Wife of a friend

A

Endometriosis

24
Q

False about Endometriosis

A

Distant sites are never involve

ex: heart and lungs

25
False about morning sickness
* Never severe enough to require hospitalization
26
What can be seen if there is disruption of pituitary stalk?
* All of the above * Increase in prolactin levels * Decrease in: * FSH secretion * ACTH secretion * Drop in LH levels
27
Flase about human placental lactogen
Protects against fetal hyperglycemia
28
False about labor?
* Well defined mechanism of delivary
29
What is Responsible for estriol production during the second and third trimesters of pregnancy?
* Placenta * Fetal Liver * Fetal Adrenal Gland
30
Most common cause of abnormal uterine bleeding
Dysfunctional uterine bleeding
31
Main cause of dysfunctional uterine bleeding?
anovulatory cycle (Failure to ovulate)
32
T or F: Adolescent girls generally start their growth spurt later than do adolescent boys.
False
33
What causes premenstrual syndrome?
decreased progesterone just before menses
34
hCG
Uncertain Physiologic role after 9 weeks gestation
35
Function of syncytiotrophoblast
* Produces human chorionic gonadotropin * Adhesion * Invasion * Phagocytosis
36
What is only secreted after implantation?
HCG
37
Most responsible for increased uttering contractibility near term in pregnany
* progesterone:estrogen ratio
38
Main source of estrogen and progesterone after 8 weeks of pregnancy:
Placenta
39
Which pituitary cell type is known to increase from 20% to 50% of pituitary volume during pregnancy?
Lactotroph
40
Blood levels of which substance are described by curve B?
Progesterone
41
What condition?
Abruptio Placenta
42
The tissue shown in this illustration is which one of the following
proliferative endometrium