Chp 1: intermediate filaments Flashcards
1
Q
Keratin / Cytokeratin
A
Epithelium
Carcinoma, so SCC would stain +
2
Q
Vimentin
A
Mesenchymal cells
Osteoblasts, chondrocytes, adiopocytes
-sarcoma would stain +
3
Q
Desmin
A
-muscles
Rhabdomyosarcoma would stain +
4
Q
GFAP
A
Neuroglia (Astrocytes + Ependymal cells )
Pilocytic astrocytoma in children would stain +
Glioblastoma in adults
5
Q
Neurofilament
A
neurons
ex= Synaptobrevin
anything neuroendocrine OR neuroblastoma (child tumor of the adrenal medulla) would stain +
6
Q
Lamin / Nuclear Lamins
A
- Found in all cells, important for nucleus morphology (nuclear membrane) + important in DNA transcription
nuclear pore would stain +
