Cholinomimetic

Question 1

What is cholinomimetics?

Answer 1

Cholinomimetics or cholinergic drugs are those drugs that cause effects similar to those resulting from introduction of acetylcholine, or simulation of ganglions of the parasympathetic nervous system. These drugs imitate action of endogenously released acetylcholine.

Question 2

What agonists are used to induce miosis? name 3

Answer 2

ACh, Carbachol, Pilocarpine (CAP)

Question 3

What agonist is used to treat glaucoma?

Answer 3

Carbachol and Pilocarpine

Question 4

What agonist is used to treat urinary retention and inadequate emptying of bladder?

Answer 4

Bethanechol

Question 5

What are the examples of direct acting agonists?

Answer 5

CAP, Bethanechol

Question 6

Cevimeline is used for

Answer 6

treatment of dry mouth and especially associated with Sjögren’s syndrome

Question 7

What agonist is used for diagnosis of bronchial hypersensitivity?

Answer 7

methacholine

Question 8

Pilocarpine can be used for two types of treatment which are

Answer 8

Glaucoma and dry mouth

Question 9

4 primary effect of ACh to CVS

Answer 9

1. Vasodilation
2. -ve chronotropic effect (reduce HR)
3. -ve dromotropic effect (reduce AV node conduction)
4. -ve inotropic ( reduce force of cardiac contraction)