Antimuscarinic

Question 1

What antimuscarinic used for?

Answer 1

to inhibit muscarinic receptor

Question 2

Antimuscarinic agents are competitive antagonist. T/F

Answer 2

T

Question 3

Examples of classic non-selective antimuscarinic?

Answer 3

Atropine and Hyocine(Scopolamine)

Question 4

Diff dose of atropine cause diff effects. explain in terms of effects on CVS.

Answer 4

At low dose, cause bradycardia because M1 blockade at inhibitory prejunctional neuron. At high dose, cause tachycardia due to M2 blockade at SA node

Question 5

Atropine cause excessive lacrimation, salivation and sweating. T/F?

Answer 5

F. cause xerostomia , reduce production of sweat in sweat gland, reduce production of tear in lacrimal glands

Question 6

What drug is used to prevent nausea and vomiting due to motion sickness?

Answer 6

scopolamine

Question 7

How atropine affect eye?

Answer 7

cause mydriasis and cycloplegia(inability to focus)

Question 8

What drug is used to treat overreactive bladder?

Answer 8

Darifenacin, oxybutynin, trospium, solifenacin, tolterodine, fesoterodine

Question 9

What drug is used to manage COPD and how it works?

Answer 9

IpraTropium, tioTropium. cause bronchodilation and reduction of mucus

Question 10

What are anticholinergic A/E?

Answer 10

ABCDS

Agitation, Blurred vision, Constipation/confusion, Dry mouth, Stasis of urine and sweating