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QUIZ 8 > Cholinergic Drugs II > Flashcards

Cholinergic Drugs II Flashcards

1
Q

muscarinic receptor antagonists

A

competitively block muscarinic receptors

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2
Q

belladonna alkaloids

A

competitive muscarinic antagonists

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3
Q

belladonna alkaloid examples

A

atropine and scopolamine

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4
Q

salivary glands (muscarinic antatgonist)

A

dry mouth; parasympathetic secretions are completely abolishes

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5
Q

sweat glands (muscarinic antagonist)

A

skin hot and dry (no sweating)

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6
Q

eyes (muscarinic antagonist)

A

dilation of pupil and relaxation of ciliary muscle

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7
Q

heart (muscarinic antagonist)

A

result in increasing tachycardia by blocking vagal effects on SA node

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8
Q

circulation (muscarinic antagonist)

A

vasoconstriction to raise blood pressure

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9
Q

respiratory tract (muscarinic antagonist)

A

inhibition of secretions (dry mucus), bronchodilation, relaxation

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10
Q

GI tract (muscarinic antagonist)

A

reduction of secretions, inhibition of motility

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11
Q

urinary tract (muscarinic antagonist)

A

urination retention

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12
Q

CNS (muscarinic antagonist)

A

decreased concentration/memory, drowsiness, excitation, hallucinations, coma

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13
Q

diagnose muscarinic antagonist poisoning

A

administer an AchE inhibitor so that more Ach will be produced and compete with atropine (or other antagonist) and there should be relief of symtpoms

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14
Q

quaternary ammonium compounds

A

antagonist that can relieve symptoms without effecting CNS but greater potency for nicotinic receptors

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15
Q

homatropine and tropicamide

A

muscarinic antagonist topical solutions for eye

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16
Q

ipratropium and tiotropium

A

muscarinic antagonists for COPD (via inhaler)

17
Q

benztropine and biperiden

A

muscarinic antagonists for Parkinson-like symptoms induced by antipsychotic therapy

18
Q

scopolamine

A

muscarinic antagonist for motion sickness

19
Q

glycopyrrolate

A

muscarinic antagonist for peptic ulcers (do have side effects since have to use such high dose to affect GI tract –> dry mouth, blurred vision, etc.)

20
Q

dicyclomine

A

muscarinic antagonist for spasticity of GI tract (IBS)

21
Q

oxybutynin, tolterodine, solifenacin

A

muscarinic antagonists for overactive bladder

22
Q

glycopyrrolate in cerebral palsy

A

can reduce excessive drooling

23
Q

atropine and scopolamine

A

muscarinic antagonists for respiratory tract that reduce secretion; used in OTC cold medicines

QUIZ 8 (10 decks)

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