Cholinergic Drugs Flashcards
1
Q
Varenicline
A
- smoking cessation
- nicotinic agonist
2
Q
Succinylcholine
A
- muscle relaxant
- nicotinic agonist
3
Q
Bethanechol
A
- post-op ileus
- muscarinic M3 agonist
4
Q
Pilocarpine
A
- Sjorgren’s syndrome (helps with dry mouth)
- muscarinic agonist
5
Q
Atropine
A
- topical for eye or reversal of cholinergic toxicity
- muscarinic antagonist
6
Q
Scopolamine
A
- topical for eye
- muscarinic antagonist
7
Q
Tropicamide
A
- topical for eye
- muscarinic M3 antagonist
8
Q
Benztropine
A
- parkinson’s tx
- muscarinic antagonist
9
Q
Ipratropium
A
- COPD
- muscarinic antagonist
10
Q
Tolterodine
A
- incontinence
- muscarinic M3 antagonist
11
Q
Edrophonium
A
- diagnostic tool for MG
- short-acting Achesteraase inhibitor
12
Q
Neostigmine
A
- tx for MG, ileus, reversal of neuromuscular blockade
- intermediate-acting inhibitor of Achesterase (0.5-2 hr)
13
Q
Pyridostigmine
A
- tx for MG
- intermediate-acting Achesterase inhibitor (3-6 hr)
14
Q
Ambenonium
A
- tx for MG
- intermediate-acting Achesterase inhibitor (4-8 hr)
15
Q
Demecarium
A
- tx for glaucoma
- intermediate-acting Achesterase inhibitor (4-6 hr)
16
Q
Physostigmine
A
- tx for glaucoma
- intermediate-acting Achesterase inhibitor
- only drug in this class that crosses BBB
17
Q
Rivastigmine
A
-derivative of physostigmine, tx for AD
18
Q
Pralidoxime
A
- antidote for cholinergic toxicity, can be given repeatedly during first 48 hours of exposure
- interacts with acetylcholinesterase blocking agent
