Cholinergic + Anticholinergic

Question 1

How do cholinergic drugs work?

Answer 1

Stimulate PNS, mimic Ach effects

Question 2

Which cholinergic drug is given for urinary retention?

Answer 2

Bethanechol

Question 3

What is the antidote for a cholinergic crisis/overdose?

Answer 3

Atropine

Question 4

How do anticholinergic drugs work?

Answer 4

Block or inhibit Ach in PNS
Allowing SNS to dominate

Question 5

How do anticholinergic drugs help a neurogenic or overactive bladder/urinary incontinence?

Answer 5

They slow parasympathetic activities like urination

Question 6

Oxybutynin
-indication?

Answer 6

Anticholinergic drug
-given for overactive bladder, neurogenic bladders

Question 7

Tolterodine
-indications?
-index?

Answer 7

Anticholinergic drug
-given for frequency, urgency, and urge incontinence

Low therapeutic index

Question 8

Older adults are very sensitive to the ______ effects of Anticholinergic drugs, can cause ______, increased risk of ____

Answer 8

CNS effects
Delirium
Heat stroke risk