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Pharm > Cholinergic Agonist > Flashcards

Cholinergic Agonist Flashcards

0
Q

Cholinergic agonist effects

A

Bradycardia, vasodilation, secretion, bronchoconstriction, miosis, voiding, sweating

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1
Q

Acetylcholine

A

Direct, non-selective, cholinergic agonist

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2
Q

DUMBBELSS: cholinergic agonist side effects

A

Diarrhea, urination, miosis, bronchospasm, bradycardia, excitation, lacrimation, secretion, salivation

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3
Q

Uses for cholinergic agonists

A

Ophthalmology, sjogrens disease, atonic ileus/bladder, myasthenia gravis, drug OD, reversal of NMJ blockade

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4
Q

Cyclospasm

A

Excess accommodation due to excessive ciliary m. Contraction

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5
Q

Drug of choice in glaucoma

A

Pilocarpine

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6
Q

Tx for glaucoma

A

Pilocarpine, echothiophate, timolol

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7
Q

Echothiophate

A

Irreversible AchE inhibitor, long lasting effects, used for glaucoma management

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8
Q

Carbachol

A

Non-selective cholinergic agonist, used to suppress IOP after cataract surgery

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9
Q

Sjogrens disease

A

AI disease with dry eyes, mouth, fatigue, joint pain, dysfunction with kidneys, GI, blood vessels, liver etc

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10
Q

Pilocarpine indications

A

Lowering IOP(DRUG OF CHOICE), glaucoma, sjogrens disease, miosis

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11
Q

Cevimeline

A

Non-selective muscarinic cholinergic agonist, TX of sjogrens

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12
Q

Selective muscarinic cholinergic agonists

A

Bethanechol, cevimeline, pilocarpine

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13
Q

Drugs for neurogenic bladder/ileus

A

Neostigmine, bethanechol

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14
Q

Drugs for Myasthenia Gravis

A

Edrophonium, neostigmine

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15
Q

Edrophonium

A

Diagnosis of myasthenia gravis, eval of MG treatment, reversal of NMJ blockage triggered by non depolarizing nic antagonists

16
Q

Neostigmine

A

Reversible AchE inhibitor, paralytic ileus tx, MG long term management,

17
Q

Treatment of anti cholinergic OD = hyperthermia, hallucinations

A

Physostigmine

18
Q

Physostigmine

A

Reversal AchE inhibitor, more in CNS than neostigmine

19
Q

Treatment of organophosphate poisoning = death, seizures, could be from echothiophate and organophosphate

A

Atropine, pralidoxime

Pharm (6 decks)

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