Cholesterol Metabolism & Lipoproteins Flashcards
1
Q
REGULATION OF CHOLESTEROL SYNTHESIS key enzyme
A
HMG-CoA reductase
2
Q
HEPATIC REGULATION OF CHOLESTEROL SYNTHESIS
A
activated by: insulin
inhibited by: glucagon and epinephrine
3
Q
activates LCAT
A
ApoA-I
4
Q
binds to LDL receptor
A
ApoB-100
5
Q
activates lipoprotein lipase
A
ApoC-II
6
Q
inhibits lipoprotein lipase
A
ApoC-III
7
Q
triggers clearance of VLDL and chylomicron remnants
A
ApoE
8
Q
chylomicrons
A
Transport of dietary lipids
9
Q
VLDL
A
Transport of triacylglycerols from liver to other tissues
10
Q
IDL
A
Metabolic intermediate
11
Q
LDL
A
Transport of cholesterol from liver to other tissues
12
Q
HDL
A
Transport of cholesterol from tissues to liver
13
Q
Cholesterol activates
A
ACAT
14
Q
Cholesterol inhibits
A
LDL receptor synthesis
HMG-CoA Reductase
