cholesterol-lqc 9b Flashcards
where is cholesterol found
in cell membranes
what is cholesterols function in the body
regulate fluidity
cholesterol is
insoluble
lipoproteins are
soluble
what is a lipoprotein
Cholesterol combined with triglycerides and protein
Which 3 molecules combine to form the lipoprotein in LDL?
Cholesterol, triglycerides and protein (lower % of protein)
Which 3 molecules combine to form the lipoprotein in HDL?
Cholesterol, triglycerides and protein (higher % of protein)
Saturated or unsaturated fatty acid in triglyceride in LDL
saturated
Saturated or unsaturated fatty acid in triglyceride in HDL
unsaturated
role in cholesterol transport in LDL
Transports cholesterol from liver to tissues, where it binds to LDL receptors (LDLR) on cell membranes to be taken up by cells (to be used in cell membranes)
role in cholesterol transport in HDL
Transports cholesterol from tissues to the liver where it is broken down. Important in decreasing blood cholesterol levels
does LDL Increases or decreases risk of atherosclerosis
Increases- Excess LDLs in blood overload LDLRs, so blood cholesterol levels increase
Cholesterol may be deposited in artery walls forming atheromas
does HDL Increases or decreases risk of atherosclerosis
Decreases- Helps remove lipid from atherosclerotic plaques
What are the consequences of increased saturated fats in the diet?
- Saturated fats may also decrease LDLR activity, so less LDLs are removed from blood.
- Blood cholesterol levels increase further
- More cholesterol deposited in artery walls, so more atheroma formation.