Cholesterol Flashcards
1
Q
where is cholesterol located
A
between membrane fatty acid chains
2
Q
what is cholesterol a precursor to
A
bile salts and steroid hormones
3
Q
where is the primary site for cholesterol synthesis
A
liver
4
Q
where is cholesterol synthesized
A
cytosol
5
Q
is HMG CoA reductase reversible
A
no
6
Q
what are the three main ingredients to make cholesterol
A
acetyl CoA, NADPH, ATP
7
Q
what is the main enzyme of cholesterol
A
HMG CoA reductase
8
Q
what is the first unique compund in cholesterol synthesis
A
mevalonate
9
Q
all bile salts end in what
A
“cholic acid” or “cholate”
10
Q
cholesterol synthesis is stimulated by
A
ATP, NADH, insulin, fructose
11
Q
cholesterol synthesis is inhibited by
A
ADP, AMP, NAD+, glucagon
12
Q
All carbons of cholesterol come from what
A
acetyl CoA
