Cholesterol

Question 1

•Cholesterol precursors converted to …….

Answer 1

Vitamin D

Question 2

Precursor to bile salts and steroid hormones

Answer 2

Cholesterol

Question 3

Cholesterol synthesis is in —-

Answer 3

Cytoplasm

Question 4

Ketone synthesis in…—

Answer 4

Mitochondria

Question 5

Rote limiting erzyne of cholesterol synthesis

Answer 5

HMG coa → mevalonic acid
HMG coA reductase

Question 6

Excess cholesterol is stored as

Answer 6

Cholesterol esters

Question 7

SLO syndrome

Answer 7

7-dehydrocholesterol deficiency
3rd common metabolism disorder in USA
Microcophaly
Syndacthey and polydachtly
Cleft plate
Hypospadias ) only males

Question 8

Only efficient way of cholesterol elimination

Answer 8

Bile

Question 9

Modified cholesterol by bacteria

Answer 9

coprostenol
and cholestanol.

Question 10

HMG COA enzyme is active when

Answer 10

Dephosphotylated

Question 11

Statin drugs are competitive inhibitors of

Answer 11

HMG coa reductase

Question 12

Primary bile acids

Answer 12

Cholic Acid and Chenodeoxycholic Acid

Question 13

Rate limiting step in bile acid
synthesis

Answer 13

7-hydroxylase

Question 14

secondary bile acids.

Answer 14

Deoxycholic acid from Cholic Acid
• Lithocholic Acid from Chenodeoxycholic acid

Question 15

Cholesterol synthesis requires

Answer 15

Nadph
O2
ATP

Question 16

first steroid compound
synthesized)

Answer 16

Lanosterol

Question 17

Excess cholesterol is stored as

Answer 17

Cholesterol esters

Question 18

Protonated form. Ionized form

Answer 18

Bile acid. Bile salt

Question 19

ate of HMG-CoA reductase is controlled by

Answer 19

sterol regulatory element binding protein (SREB

Question 20

Enzyme 7-hydroxylase requires

Answer 20

O2 NADPH cytochrome P450