Adipose Tissue Biochemistry Flashcards

1
Q

2 types of adipose tissue ?

A

White adipose tissue
Brown adipose tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

…………. restricts lipolysis under basal conditions

A

Peilipin 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

↑ TNF -alpha and IL-6

A

Loss of perilipin 1 → obesity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Primary function of bat

A

Non shivering thermogenesis with UCP -1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Beige adipocytes derived from —-

A

WAT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cell signaling proteins secreted by adipose tissue

A

Adipokines
Adipocytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Adipokines

A

Leptin
Adiponectin
TNF -a
Il-6
Plasminogen activator inhibitor (pai-1)
MCP -I
RBP -4
Visfatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In obese resistin is

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Adipsin levels are low in patients with —-

A

Anorexia nervosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cause of insulin resistance

A

TNF a
IL6
Nefa
Resistin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Improve insulin resistance

A

Leptin
Adiponectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

………….metabolic syndrome, vascular thromboembolic events, and acute coronary syndrome.

A

PAI1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

innate immunity

A

Visfatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Leptin ………… body weight

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Wat stores

A

Triglycerides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Increases nitric oxide (NO)
production in endothelial cells.

A

Apelin

17
Q

Serum PAI-1 levels decrease with

A

weight loss, and metformin therapy.

18
Q

PAI-1 is increased in

A

Metabolic Syndrome, vascular thromboembolic events, and
acute coronary syndrome.

19
Q

Its major function is related to energy metabolism and innate immunity and it
is regarded as a pro-inflammatory adipocytokine.

A

Visfatin

20
Q

It induces leukocytes and stimulate production of TNF-α and IL-6.

A

Visfatin