CHOLESTEROL Flashcards

1
Q

What are the 5 statins?

A
  1. ATORVAstatin
  2. LOVAstatin
  3. PRAVAstatin
    4.ROSUVAstatin
  4. SIMVAstatin
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2
Q

Statins are prescribed to prevent _________?

A
  1. heart attack
  2. stroke
  3. prescribed following a heart attack or stroke to prevent subsequent events
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3
Q

_______ is essential building block for cholesterol

A

MEVALONATE

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4
Q

What are the 3 side effects of statins?

A
  1. Hepatotoxicity
  2. Myopathy (muscle weakness)
  3. Rhabdomyolysis
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5
Q

What happens when rhabdomyolysis occurs as the muscle cell starts dying?

A

MYOGLOBIN and Creatine Kinase (CK) leak into the bloodstream causing damage to the KIDNEYS

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6
Q

Patient education for a client taking STATINS?

A

report unexplained muscle aches

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7
Q

What are the signs of Rhabdomyolysis?

A
  1. Muscle Pain
  2. Dark Urine
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8
Q

Which time of the day should you take STATINS?

A

at NIGHT

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9
Q

Why should you avoid GRAPEFRUIT [juice]?

A

it cause statin level to be too HIGH

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10
Q

What are the contraindication of STATINS?

A
  1. Liver dx
  2. Pregnant
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11
Q

This medication is added to the statin to lower cholesterol?

A

EZETEMIBE

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12
Q

What are the 2 fibrates?

A
  1. FENOfibrate
  2. GEMfibrozil
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13
Q

Fibrates are prescribed for patients with _____?

A

High Triglyceride (VLDL) and LDL

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14
Q

What are the 4 adverse effects of FIBRATES?

A
  1. Myopathy
  2. Hepatotoxicity
  3. Gallstone
  4. Diarrhea
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