cholangiocarcinoma Flashcards
1
Q
What is it?
A
Carcinoma of epithelial cells of bile duct
2
Q
What type are most cholangiocarcinomas?
A
Adenocarcinoma
3
Q
Anatomy of bile duct from ascending to descending
A
Right and left hepatic duct Common bile duct Gall bladder Pancreatic duct Ampulla of vater Duodenum
4
Q
Where do most cholangiocarcinomas occur?
A
Confluence of right and left hepatic ducts.
Klatskin tumours
5
Q
Main RF of cholangiocarcinoma?
A
Primary sclerosing cholangitis
6
Q
Presentation? (3)
A
Painless obstructive jaundice
Non-palpable gall bladder
FLAWS
7
Q
App Ix
A
LFTs
ERCP
Look for CA 19-9 antigens (elevated in cholangiocarcinoma)
8
Q
Mx? (1)
Is there curative treatment?
A
No curative treatment
ERCP and place stent for symptom relief» will allow bile to travel more freely through duct
9
Q
Signs on PE?
A
Palpable mass in RUQ due to proliferated bile duct
