CHO ingestion / Fasting Flashcards
Omega-3
Plays important role on the following areas
- Alzemers, Dementia and Cognative function
- Age related macular degestion
- Cardio vascualr disease
- Cancer prevention
- Rheumatoid arthritis
Intermittent fasting
Majority of humans cannot sustain Calorie Restriction CR for long periods
IF improves cardio metabolic risk factors (insulin resistance, inflammation, decreases visceral fat mass)
Similar weight loss as CR regiments
Metabolic switch: Use of glucose to fatty acid‘s and fatty acid delivered
Time restricted feeding prevent adverse effects of a high fat diet on cycle AMP response
Crucial role in glucogenesis during fasting
Inflammation in the intestines appears to be reducedby IF
CHO ingestion
As time increases during exercise FFA concentration increases meaning FFA oxidation decreases.
CHO oxidation rapidly increases after ingestion compared to placebo’s.
Muscle glycogen decreases in parallel to CHO oxidation
Insulin stimulation
Insulin stimulation a cascade of PRO causes GLUT-4 transport proteins to plasma membrane
AMPK
https://www.youtube.com/watch?v=4G56m9fyNWY
Insulin resistance
Insulant resistance = increase adipose tissue release | Increased IpI activity and FFA availability | Direct IMTG inhibition liberation | Exacerbated by IMTG decreased turnover | FFA entry to energy stores
Acpimax
Drug not natural
Acctylcarartine
Facilitates movement of ACET?? cOA during fat oxidation
Acpimax increases what two things?
IMTG utilisation
Insulin sensitivity
Increased acctylcarnitine inhibits what?
CPT1 (FA entry into the mitochondria)
Decreased acctylcarnitine increases what?
Fat oxidation
Mechanisms of fatigue
Limitations in energy supply (PCr resynthesis, anaerobic/aerobic glycolysis, phosphocreatine availability, glycogen availability)
Metabolic accumulation (oxygen availability)
