Inflammation + Metabolic Disease

Question 1

What is inflammation?

Answer 1

Bodies defence to infection/injury

Question 2

How does inflammation work?

Answer 2

Leukocytes go to infected area or pathogens (pathogens cause viruses, parasites and fungi)

Question 3

What are the 4 R’s

Answer 3

Recognition

Recruitment

Removal

Repair

Question 4

What is the role of Recognition in inflammation?

Answer 4

Receptors recognising damaged cells, once detected cytokines released

Question 5

What is the role of Recruitment in inflammation?

Answer 5

Cytokines release protein molecules (selectins) which recruit leukocytes from blood stream

Question 6

What is the role of Removal in inflammation?

Answer 6

Neutrophils and Macrophages remove pathogens by engulfing damaged cells

Question 7

What is the role of Repair in inflammation?

Answer 7

Cytokine release initiates tissue repair cells

Question 8

What are 5 signs of acute inflammation?

Answer 8

1. Heat
2. Redness
3. Swelling
4. Pain
5. Loss of Function

Question 9

Chronic Inflammation has a ______ onset and duration is _____/______

Answer 9

Gradual —- Months/Years

Question 10

Obesity % in the UK in adults

Answer 10

63%

Question 11

Obesity causes insulin resistance by affecting what?

Answer 11

Insulin sensitive tissue

Question 12

Skeletal muscle, Adipose Tissue and Liver are all effected by?

Answer 12

Obesity

Question 13

4 nutritional manipulations that can reduces chronic inflammation?

Answer 13

1. Vitamin D
2. Omega-3
3. Mediterranean diet
4. Anthocyians