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PoD Test 2 > Chlamydia Trachomatis and Mycoplasma Pneumoniae > Flashcards

Chlamydia Trachomatis and Mycoplasma Pneumoniae Flashcards

1
Q

How is C. trachomatis transmitted?

A

Sexually transmitted

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2
Q

What type of cells express receptors for elementary bodies?

A

Nonciliated columnar, cuboidal, and transitional epithelial cells

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3
Q

What are the clinical manifestations of C. trachomatis caused by?

A

Direct destruction of cells during replication

Pro-inflammatory cytokine response they stimulate

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4
Q

What is the leading cause of preventable blindness in the world?

A

Trachoma

Infections predominantly in children

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5
Q

What are the two phases of infection of trachoma?

A

Active - often asympomatic

Cicatricial disease - conjuctiva inflammation and eyelid scarring, scarring leads to entropian and trichiasis

Trichiasis leads to corneal abrasion and scarring and blindness

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6
Q

What is the presentation of chlamydia cervicitis?

A

Mucopurulent discharge is visible

Cervix is erythematous and friable

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7
Q

What is newborn inclusion conjunctivits?

A

Caused by chlamydia when infant passes through infected birth canal

Swollen eyelids, hyperemia and purulent discharge

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8
Q

What is adult inclusion conjunctivitis?

A

Genital infection precedes eye involvement

Mucopurulent discharge, keratitis, corneal infiltrrates and scarring

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9
Q

What is Reiter syndrome?

A

Urethritis, Conjunctivitis, Polyarthritis

Typically occurs in young men

Caused by C. trachomatis

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10
Q

What is infant pneumonia?

A

Rhinitis initially then staccato cough and tachypnea, afebrile

CXR shows bilateral interstitial infiltrates

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11
Q

What is Parinaud oculoglandular syndrome?

A

Caused by LGV serotypes

Conjunctival inflammation with perauricular, submandibular, and cervical lymphadenopathy

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12
Q

What is the diagnosis for LGV POS?

A

Antigen detection

Nucleic acid assays (NAAT)

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13
Q

What is terminal adhesion protein P1?

A

Binds glycoprotein receptors of base of cilia of epithelial cells

M. pneumoniae

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14
Q

What clinical syndromes can be caused by M. pneumoniae?

A

Mild UTRI

Otits Media

Tracheobronchitis

Pneumonia - most common cause of atypical case

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15
Q

What is erythema multiforme?

A

Targetoid rash due to central epidermal necrosis surrounded by erythema

Most commonly associated with HSV, can also be caused by mycoplasma

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16
Q

What is stevens-Johnson syndrome?

A

Erythema multiforme with oral mucosa/lip involvement and fever

Caused by ADR usually

17
Q

What is the lab diagnosis for M. pneumoniae?

A

Serology, enzyme immunoassays for IgM and IgG

Paired sera to confirm

18
Q

What is the treatment for M. pneumoniae?

A

Macrolides, tetracyclines, and flouroquinolones

PoD Test 2 (23 decks)

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