Chlamydia infections

Question 1

What are the pathogenic types of Chlamydia?

Answer 1

Family of gram-negative, obligate intracellular bacteria that includes 3 organisms pathogenic to humans: Chlamydia trachomatis, Chlamydophila pneumoniae, and Chlamydophila psittaci

Question 2

What are the symptoms of Chlamydial genitourinary infections?

Answer 2

Majority asymptomatic
(Muco)purulent vaginal discharge / Intermentsrual bleeding / Post-coital bleeding
Dysuria, polyuria, dyspareunia
Pelivc inflammatory disease

Question 3

How is Chlamydia diagnosed?

Answer 3

(1st) Nucleic acid amplification tests (NAAT) (i.e. PCR)

(2nd) Antigen detection

Question 4

What is the treatment for Chlamydia?

Answer 4

Azithromycin / doxycycline

Treat sexual partner as well

Question 5

What are the complications of Chlamydia?

Answer 5

PID
Ectopic pregnancy
Infertility
Reactive arthritis
Perinatal transmission of infection to the newborn

Question 6

What is Lymphogranuloma venereum?

Answer 6

Caused by Chlamydia trachomatis

Painless genital ulcers that heal spontaneously. Can lead to abscess formation and chronic lymphedema

Question 7

What are the clinical features of lymphogranuloma vernereum?

Answer 7

(Primary infection) painless, herpetiform ulcers

(Secondary infection) painful lymph nodes in the inguinal region

Question 8

What is the treatment for lymphogranuloma vernereum?

Answer 8

Doxycycline / erythromycin