Chimiothérapie Flashcards

1
Q

Molécules causant de la neurotoxicité

A
  • Vincristine
  • Platine
  • taxanes
  • Bortezomib
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2
Q

Rituxan:
Classe
Effets secondaires

A

Anti-CD20

  • Réactions infusionnelles
  • Réactivation Hépatite B
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3
Q

Effets secondaires de la cytarabine haute dose

A

Toxicité cérébelleuse

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4
Q

E2 anthracyclines (-rubicine)

A

CMP irréversible
LMA secondaire

  • Néo sein
  • CHOP
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5
Q

E2 platins

*E2 Cisplatin

A

Tous donnent neuropathie périphérique

Cisplatin hautement émétique, néphrotoxique, ototoxique, hypoMg/Ca/K

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6
Q

E2 taxanes

-taxel

A

Neuropathie périphérique
Alopécie
Myalgies

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7
Q

E2 vinca alcaloides

Vinorelbine, Vincristine

A

Neuropathie périphérique

  • CHOP
  • Néo poumon
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8
Q

E2 cyclophosphamide

A

Émétique
Cystite hémorragique, Néo vessie
Néo secondaire (LMA, SMD)
Infertilité

*CHOP

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9
Q

E2 anti-angiogénèse (Bevacizumab-Avastin)

A

HTA
Saignement
Delayed wound healing
Thromboembolie artérielle (IDM-AVC)

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10
Q

E2 inhibiteurs de la tyrosine kinase (sunitinib-Sorafenib)

A
HTA
Saignement
Réaction cutanée main-pied
Diarrhée
Mucosite
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