childhood infection diseases Flashcards
What is the leading cause of childhood mortality worldwide?
pneumonia
what is bronchiolitis?
viral infection primarily affects infants and young children. Respiratory syncytial virus (RSV) is a common cause, and outbreaks can occur seasonally
(Glasper,2016)
name two gastrointestinal infections
- rotavirus
- gastroenteritis
(Cherry et al, 2019)
name two vector-borne infections
- malaria
- dengue fever
(Cherry et al, 2019)
name three vaccine-preventable infections
- measles
- polio
- MMR
(Cherry et al, 2019)
how many children worldwide have RSV?
33 million under 5yrs
(Cherry et al, 2019)
how long is the TB incubation?
3-9 months
(Cherry et al, 2019)
what is the incubation period of polio?
usually 7 - 10 days but can range from 4 - 35 days
(Cherry et al, 2019)
how does polio enter the system?
mouth/intestine - invades nervous system
(Cherry et al, 2019)
what are symptoms of polio?
- fever
- fatigue
- headache
- vomiting
- pain in limbs
- permanent muscle paralysis can occur
(Cherry et al, 2019)
how is polio spread?
faeces, can spread quickly through areas with poor hygiene and sanitation systems
(Cherry et al, 2019)
what is infectivity?
associated with length of pre-symptomatic phase
(Cherry et al, 2019)
what is pathogenicity?
the process by which an infection leads to a disease
(Cherry et al, 2019)
what are the 4 stages of pathogenicity?
- portal of entry
- local replication
- spread to target organs
- shedding to environment
(Cherry et al, 2019)
what is virulence?
how harmful a pathogen is
(Cherry et al, 2019)
list the 4 parts of virulence
- viral replication
- impact on host defence mechanism
- tropism - spread and transmission through body
- encodes for products that are directly toxic
(Cherry et al, 2019)
what is immunogenicity?
the ability of a foreign antigen to provoke an immune response
(Cherry et al, 2019)
what are the four host factors?
- age
- immunity
- genetics
- external factors
(Cherry et al, 2019)