Chest pain in children and adolescents–understanding the differential diagnosis and evaluation Flashcards
What percentage of children complain of chest pain?
98%
What is the prevalence of a cardiac origin in children who present with chest pain?
Less than 6%
What is the differential diagnosis for child presenting with chest pain?
- Musculoskeletal
- Pulmonary
- Gastrointestinal
- Miscellaneous
- Cardiac
What are the signs and symptoms, physical findings and lab imaging findings for musculoskeletal chest pain?
Signs symptoms history: Reproducible chest pain on the rib cage
Physical exam: Point tenderness that can develop gradually or started suddenly
Imaging: Chest x-ray to look for bony lesions
What are the signs and symptoms, physical findings and labs/imaging findings or evaluation for pulmonary origin of chest pain?
Signs symptoms: Increased work of breathing, increased cough, dyspnea, severe sudden chest pain
Physical findings: Wheezing, crackles, rhonchi, hypoxia
Chest x-ray or imaging: Lung pathology, collapsed lung or radiodensity
What are the signs/symptoms, physical findings and lab/imaging findings or evaluation for gastrointestinal origin of chest pain?
Signs/symptoms: Chest pain associated with certain foods or medications, pain improves after taking in an acid
Physical exam: Pain in the right upper quadrant that can spread to the right shoulder blade or back, burning epigastric pain
Labs/imaging: H. pylori testing
What are the signs/symptoms, physical findings and lab/imaging findings or evaluation for miscellaneous origin of chest pain?
Signs/symptoms: Chest pain associated with precipitating stressful events, recurrent somatic complaints, lightheadedness, and paresthesias
Physical exam: Chest pain associated with numbness, weakness, or vesicular rash
Labs/imaging: Tests cluster of vesicles for herpes and MRI of spine if chest pain associated with numbness or weakness
What are the signs/symptoms, physical exam, lab/imaging findings or evaluation for any inflammatory cardiac origin of chest pain?
Signs/symptoms: Sharp chest pain, palpitations, and shortness of breath
Physical findings: This and for murmurs or arrhythmias
Labs/imaging: Chest x-ray, ECG, and echo
What are the signs/symptoms, physical exam, lab/imaging findings or evaluation for a cardiac origin of chest pain involving increased myocardial demand or decreased supply?
Signs/symptoms: Family history of genetic or connective tissue disorder (Marfan syndrome) and palpitations
Physical exam heart murmur or arrhythmia
Labs/imaging: Chest x-ray, ECG, and echo
What are the signs/symptoms, physical exam, labs/imaging findings were evaluation for a cardiac origin of chest pain due to coronary artery abnormalities?
Signs/symptoms: Chest pain with history of Kawasaki disease, COVID-19, coronary vasculopathy and heart transplant patient.
Labs/imaging chest x-ray, ECG, and echo
What are the signs/symptoms, physical exam, lab/imaging findings or evaluation for a cardiac origin of chest pain due to miscellaneous cardiac causes?
Signs/symptoms: Sudden severe, sharp pain in chest or upper back
Physical exam: Heart murmur, low blood pressure, rapid weak pulse
Chest x-ray, EKG, and echo.
What are the signs/symptoms, physical exam, lab and imaging findings for a cardiac origin of chest pain due to drugs?
Signs/symptoms: Chest pain with tobacco smokers, cocaine, and other sympathomimetic drugs
Physical exam: Vasoconstrictive activity of drugs lead to myocardial ischemia
Labs/imaging: Chest x-ray, EKG, and echo
What are the 7 items in the musculoskeletal differential for noncardiac chest pain?
- Costochondritis
- Tietze syndrome
- Slipped rib syndrome
- Trauma/muscular strain/overuse injury
- Xiphoid pain or xiphoidalgia
- Sickle cell vaso-occlusive crisis
- Nonspecific/idiopathic
What are the 8 subcategories of pulmonary differential for chest pain?
- Bronchial asthma
- Exercise-induced/cough variant asthma
- Bronchitis
- Pleurisy
- Pneumonia
- Pneumothorax
- Pulmonary embolism
- Acute chest syndrome (a potential fatal complication of sickle cell disease and is accompanied by fever, respiratory symptoms, and new radiodensity on chest x-ray)
What are the 5 subcategories for the gastrointestinal differential diagnosis of chest pain?
- GERD
- Esophageal spasm
- Peptic ulcer disease
- Drug-induced esophagitis/gastritis
- Cholecystitis