Chemotherapy Flashcards

1
Q

Vilka faser är chemo superbra?

A

S/M fas

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2
Q

Antimetaboliter

A

S fas: Purine och pyramidine analog

Folate acid analog

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3
Q

Topoisomerashämmare

A

S Fas: Hämmar topoisomeras 1/2

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4
Q

Antimicrotubili

A

M fas: Hindrar formation/disambly av MT

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5
Q

Antitumorantibiotika:

A

Cell cycle independent: Cytotoxist bland annat genom fria radikaler

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6
Q

Alkilating agents

A

binder covalent alkylgrupp på DNA

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7
Q

Monoklonal antibodies

A

Mimik antikroppar och sätter på målcellen.

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8
Q

Hormontherapy

A

Sänker östrogen

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9
Q

Vanliga bieffekter:

A

FFa snabbt delande celler: Neutropenic enterocolitis(typhlitis), Tumor lysis syndrom

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