Antibiotika Flashcards

1
Q

Karatäristika för antibiotik

A

Toxisk för målbakterien men ofarlig för människan,
Vara aktiv tillräckligt länge för att kunna påverka baterien,
Nå området där bakterien finns
Bakterien behöver vara känslig mot antibiotikan.

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2
Q

Två typer av antibiotika

A

bateriocidal/bateriostatica

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3
Q

Grampositiv/gramnegativ bakterie

A

Pos: peptidoglycan + plasmamembran
Neg: Yttermembran + pepidoglycan + plasmamembran

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4
Q

Mekanismen bakom B-laktamer

A

Förhindrar cellväggssyntes, ex Pencillin

funkar på gramnegativ occ pos

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5
Q

Mekanism bakom glycopeptides

A

Vancomysin binder till D-ala-D-ala, gram positiv

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6
Q

Mekanism bakom Polymycin

A

Gram negativ, polymyxin rubbar cellväggarna.

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7
Q

Aminoglycosides

A

Gör så att 30s subenheten läser fel antikodon -> proteinet blir whack

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8
Q

Tetracylkin

A

Blockerar bindingsite för tRNA

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9
Q

Microlides

A

förhindrar peptidbindning

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10
Q

Chloraphenicol

A

Binder till 50s

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11
Q

Flouroquinolores

A

Inhibit DNA replikation

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12
Q

Folate antagonister

A

Inhiberar syntes av puriner

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