Chemo, radiotherapy and immunotherapy Flashcards

1
Q

What medication can be given to relax patients before radiotherapy?

A

Lorazepam (0.5mg, 1/2 hour before)

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2
Q

Immunotherapy agents examples

A

Anti-CTLA-4

Anti-PD-1

Anti-PD-L1

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3
Q

Symptoms of immunotherapy toxicity

A

Fatigue

Fevers

All the itis

  • Diarrhoea (colitis)
  • Thyrodiits
  • Pancreatitis
  • Uveitis
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4
Q

BRAF mutation is associated with what cancer?

A

Melanoma

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5
Q

Side effects of chemotherapy

A

Bone marrow suppression

Nausea/ vomiting

Hair loss

Mucositis

Infertility

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6
Q

Toxicity effects of asparagine

A

Neurotoxicity

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7
Q

Cisplatin toxiity

A

Ototoxicity

Nephrotoxicity

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8
Q

Vinscristine/ vinblastine toxicity

A

Peripheral neuropathy

Myelosuppression

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9
Q

Bleomycin toxicity

A

Pulmnonary fibrosis

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10
Q

Doxorcubin toxicity

A

Cardiotoxicity

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11
Q

Cyclophosphamide toxicity

A

Bladder/ kidneys

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12
Q

Methotrexate toxicity

A

Nephrotoxic

Myelosuppression

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13
Q

Late side effects of radiotherapy

A

Infertility

Cervical strictures

Bladder dysfunction

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