Chemo Flashcards

1
Q

5-Fluorouracil

A

Antimetabolite->Fluoropyrimidines

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2
Q

Capecitabine

A

Antimetabolite->Fluoropyrimidines

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3
Q

Cytarabine

A

Antimetabolite->Cytidine Analogs

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4
Q

Gemcitabine

A

Antimetabolite->Cytidine Analogs

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5
Q

Azacytidine/Decitabine

A

Antimetabolite->Cytidine Analogs

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6
Q

Mercaptopurine/Thiguanine

A

Purine Antimetabolites

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7
Q

Fludarabine

A

Purine Antimetabolites

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8
Q

Cladribine

A

Purine Antimetabolites

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9
Q

Pentostatin

A

Purine Antimetabolites

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10
Q

Methotrexate/Pemetrexed

A

Antifolates

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11
Q

Vincristine, Vinblastine, Vinorelbine

A

Microtubule-Targeting Drugs ->Vinca Alkaloids (inhibits assembly)

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12
Q

Paclitaxel

A

Microtubule-Targeting Drugs ->Taxanes (inhibits disassembly)

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13
Q

Docetaxel

A

Microtubule-Targeting Drugs ->Taxanes(inhibits disassembly)

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14
Q

Ixabepilone

A

Microtubule-Targeting Drugs ->Epothilone(same MOA as Taxanes)

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15
Q

Estramustine

A

Microtubule-Targeting Drugs -> (inhibits assembly and causes their disassembly)

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16
Q

Topotecan, irinotecan

A

Topoisomerase Inhibitors-> Camptothecin Derivaties

17
Q

Etoposide, Teniposide

A

Topoisomerase Inhibitors-> (inhibits topo II)

18
Q

Doxorubicin, Daunorubicin, Idarubicin, Epirubicin

A

Topoisomerase Inhibitors-> Anthracene Derivatives

19
Q

Mitoxantrone

A

Topoisomerase Inhibitors-> Anthracene Derivatives

20
Q

Cyclophosphamide, ifosfamide

A

Alkylating Agents->Nitrogen mustard derivatives

21
Q

Bendamustine

A

Alkylating Agents->Nitrogen mustard derivatives

22
Q

Carmustine, lomustine

A

Alkylating Agents->Nitrosureas

23
Q

Cisplatin, Carboplatin, oxalaplatin

A

Heavy Metals-> Platinum

24
Q

Bleomycin

A

Miscellaneous Agent

25
Q

Hydroxyurea

A

Miscellaneous Agent

26
Q

Asparaginase

A

Miscellaneous Agent

27
Q

Arsenic Trioxide

A

Miscellaneous Agent

28
Q

Vorinostat

A

Miscellaneous Agent

29
Q

Rituximab

A

MoABs

30
Q

Ibritumomab

A

MoABs

31
Q

Tositumomab

A

MoABs

32
Q

Alemtuzumab

A

MoABs

33
Q

Cetuximab

A

Epidermal Growth Factor Receptor Ligand

34
Q

Panitumumab

A

Epidermal Growth Factor Receptor Ligand

35
Q

Trastuzumab

A

Epidermal Growth Factor Receptor Ligand

36
Q

Erlotinib

A

Epidermal Growth Factor Receptor Ligand

37
Q

Lapatinib

A

Epidermal Growth Factor Receptor Ligand

38
Q

Bevacizumab

A

Vascular Endothelial Growth Factor

39
Q

Sunitinib, Sorafenib

A

Vascular Endothelial Growth Factor