Chemical Senses Flashcards

1
Q

Which channels are activated by temperature and spicy foods?

A

TRP channels

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2
Q

What is the lowest concentration at which humans can detect odorants?

A

10^-14 M

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3
Q

Condition involving selective olfactory defecits?

A

Anosmias

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4
Q

What is the function of the Vomeronasal organ?

A

Detection of pheremones in animals.

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5
Q

Which glands secrete mucus into the nasal cavity?

A

Bowman’s Glands

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6
Q

How often do olfactory receptor cells turn over?

A

6-8 weeks

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7
Q

What are the 4 areas where the olfactory nerve projects?

A
  1. Piriform Cortex
  2. Olfactory Tubercle
  3. Amygdala
  4. Entorhinal Cortex
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8
Q

Where do fibers from the piriform cortex project and what is their function?

A

Orbitofrontal cortex for olfactory perception and identification.

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9
Q

Where do fibers from the olfactory tubercle project and what is their function?

A

Thalamus, for olfactory perception and identification.

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10
Q

Where do fibers from the amygdala project and what is their function?

A

Hypothalamus for motivation/emotion

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11
Q

Where do fibers from the entorhinal cortex project and what is their function?

A

Hippocampal formation, for olfactory memories.

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12
Q

What has increased sensitivity during an emotional state activated by epinephrine?

A

Olfactory receptors.

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13
Q

What has increased sensitivity when your hungry?

A

Locus Ceruleus activates the olfactory bulb.

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14
Q

What are the 3 types of papillae on the tongue and where are they?

A

Fungiform –> anterior tongue
Foliate –> Lateral aspect of tongue
Vallate –> in a “V” pattern on posterior tongue

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15
Q

Which nerves innervate the taste buds?

A

Facial, glossopharyngeal, vagus.

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16
Q

Where is taste information projected?

A

Ventral Posterior Medial Nucleus of the thalamus.

17
Q

What channels are on salt taste buds?

A

Amiloride sensitive Na+ Channels

18
Q

What channels are on sour taste buds?

A

H+ activated channel

19
Q

What channels are on bitter taste buds?

A

TR2 G protein Coupled Receptor

20
Q

What channels are on sweet taste buds?

A

G protein coupled receptor

21
Q

What hormones are elevated with increased appetite, and increase taste receptor sensitivity?

A

Serotonin and cholecystokinin (CCK)

22
Q

What hormones increase olfactory cell response to salt?

A

Aldosterone and vasopressin

23
Q

What is the order of projections of taste information?

A
  1. ) Nucleus of solitary tract.
  2. ) Ventral Posterior Medial Nucleus of Thalamus.
  3. ) Gustatory cortex at insula.
24
Q

What is the name of the property alowing the gustatory cortex neurons to each respond to different tastes?

A

Across fibre pattern.

25
Q

Which two diseased reduce olfactory capacity?

A

Atrophic Rhinitis and Diabetes

26
Q

What disease produces reduced olfaction AND gustation?

A

Chronic Renal Failure

27
Q

Which disease causes loss of olfactory receptor cells?

A

Alzimers

28
Q

Which diseases can enhance olfaction and gustation

A

Epilepsy and CF