Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Chemical Pathology > Flashcards

Chemical Pathology Flashcards

1
Q

When mineral levels in the blood are too high, bones absorb some of them and store them as?

A

Mineral salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Why are the bones hard?

A

Because they serve as the storage site for mineral salts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does the body maintain mineral homeostasis?

A

Sores in excess as mineral salts
And released back in the blood during deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the major mineral constituents of bone?

A

Calcium and phosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are The lost important minerals for general cellular function?

A

Calcium and phosphates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the percentage bone storage for calcium and phosphate respectively?

A

98% of 1-2 g (calcium)
85% of 1kg (phosphorus)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the agents responsible for bone mineral homeostasis?

A

Hormonal
Non-hormonal agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Principal and secondary agents fall under which class of homeostatic agent?

A

Hormonal agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Fibroblast growth factor, Parathyroid hormone, Vitamin D are all agents belonging which class?

A

Principal hormonal agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Salmon injection, glucocorticoids, oestrogen, bisphosphonate,. Pick the odd one out.

A

Bisphosphonate is a non-hormonal agent for calcium homeostasis.

Calcitonin also known as salmon injection, estrogen and glucocorticoids are secondary hormonal agents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which non hormonal agents produces a profuse decrease in the ruffled borders of osteoclasts thereby diminishing respective activity?

A

Calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Selective oestrogen receptor mediator is a secondary hormonal agent. T/F

A

False. Selective estrogen receptor mediator is a non-hormonal agent. It is not the same as estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How many as does PTH have?

A

84aa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is done prior to the release of PTH

A

Removal of 115aa and 31aa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the role of calcium sensitive protease in bone mineral homeostasis

A

It clears the intact PTH in the PTG into fragments and limits its production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Reduction in PTH production by a calcium stimulant is done by?

A

Calcium sensing receptor

17
Q

Which enzyme in the PTG produces the active metabolite of vit.D (1,25dihydroxy vit D) and what is the resultant effect?

A

CyP27B1. Suppression of PTH prod.

18
Q

What are the three entities that play a role in the inhibition of PTH production?

A

Calcium sensitive protease»>clearing of intact PTH
Calcium sensing receptor&raquo_space;reduction of PTH prod and secretion
Vit D receptor and CYP27B1 that produces the active metabolite of vit. D»»suppression of PTH production

Pharmacology (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions