CHD

Question 1

Nitrates (vasodilators)

Answer 1

GTN spray, fast acting, Work by ↑ cGMP (in muscle cells) = Muscle relaxes = (vessel dilates)
Nitrovasodilators DILATE both arteries AND veins

Question 2

Side effects

Answer 2

Headache, dizzy, lower BP with other drugs (contraindication)

Question 3

Statins

Answer 3

HMG-CoA red‘ase inhibitor reduce cholesterol synthesis LDLs! Few side effects can be GI