Antiemetics Flashcards
CNS - CTZ what type of sickness does it treat?
Drugs, toxin, chemo
Vagal what type does it treat?
GI tract
Vestibular what does it treat?
Ear, vertigo, motion sickness!
Vestibular targets?
H1 and H3 Histamine and Muscarinic (Ach)
Vagal targets?
Serotonin - 5H3T
CTZ targets
D2, Substance P (late phase)
Cyclizine what is it used for?
Motion sickness, H1, Vestibular
Bethahistine what is used for?
Vertigo H3, vestibular
AZINES like Phenothiazines are what and used for what?``
D2, treatment of drug and chemo emetics CNS/CTZ
Domperidone what is it?
D2, oral, cancer works on CNS/CTZ
Ondansertron, Gastronsetron
Serotonin 5HRT, Vagal Gastroenteritis
PITANT drugs what are they? What are they used for?
Substance P drugs, late phase CTZ emetic