chapters 12 and 13 Flashcards
_____ ____ tested for in pregnant women
cystic fibrosis
cystic fibrosis is what kind of genetic disorder?
autosomal recessive
BRCA is what kind of genetic disorder?
autosomal dominant
what kind of genetic disorder is hemophilia?
X-linked recessive
in __ _____ ______ disorders most affected people have unaffected parents
x-linked recessive
____ ____ tied to chronic myeloid leukemia
Philadelphia chromosome
____ illicit an immune response
antigens
____ immunity is present at birth
innate
_____ immunity is 1st line of defense
innate
getting an infection is an example of what type of immunity?
natural active immunity
breastmilk transfer from mother to child is an example of what type of immunity?
natural passive
vaccines are an example of what type of immunity?
artificial active
injection of serum w antibodies from 1 person to another person who doesn’t have antibodies is what type of immunity?
artificial passive
___ cells capture antigens when immune response is activated
dendritic
detrimental effects of cytokines include:
chronic _____
_________ diseases
______
inflammation
autoimmune
sepsis
____ act as messengers between cells
cytokines
____ inhibits viral replication
interferon
interferon has a _____-__________effect on cells
anti-proliferative
IL-____ is a pro-inflammatory mediator
1
IL-____ activates T cells
2
IL-___is a hematopoietic growth factor
3
IL-___ stimulates growth of mast cells
4
IL-____ is responsible for B cell and eosinophil growth and differentiation
5
IL-_____ induces fever
6
_____ ____ _____ promotes immune and inflammatory responses
tumor necrosis factor (TNF)
what 2 cells are involved in cellular immunity?
macrophages
T cells
what cell is involved in humoral immunity?
B cells
main product of secondary immune response
IGG
main product of primary immune response
IGM
elevated ____ is due to exposure to an allergen
IGE
____ is the first line of defense against protection from microorganisms
IGA
what type of lymphocytes are responsible for cell mediated immunity?
T lymphocytes
what type of lymphocytes are responsible for humoral immunity?
B lymphocytes
___ are elevated w leukemia
basophils
