Chapter5 Flashcards

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1
Q

Phospholipid

A

Phospholipids belong to the lipid family of biological polymers. A phospholipid is composed of two fatty acids, a glycerol unit, a phosphate group and a polar molecule.

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2
Q

Amphipathic

A

An amphipathic molecule is polar at one end and nonpolar at the other. They interact in specific ways when placed in an aqueous environment

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3
Q

Hydrophobic

A

nonpolar substances that are excluded by water and other polar molecules

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4
Q

Hydrophilic

A

Polar molecules that associate readily with water

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5
Q

Bilayer

A

A double layer of phospholipids in which the tails face inwards and are hydrophobic and the phosphate groups face outwards and are hydrophilic. This allows for the membrane to be selectively permeable.

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6
Q

Micelle

A

A sphere composed of a single layer of lipid molecules

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7
Q

Fatty acid

A

One of two components of a neutral lipid, containing a single hydrocarbon chain with a carboxyl group linked at one end.

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8
Q

Unsaturated hydrocarbon

A

hydrocarbons with one or more doubles bonds linking the carbons. This makes the melting point go down.

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9
Q

Saturated hydrocarbon

A

Hydrocarbons with only single bonds linking the carbon atoms. This makes the melting temperature higher.

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10
Q

Desaturase

A

Bacteria, Plants and Animals use desaturase enzymes to alter their membrane fatty acids in response to their environment. A fatty acid desaturase is an enzyme that removes two hydrogen atoms from a fatty acid, creating a carbon/carbon double bond.

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11
Q

Sterol

A

Steroid with a single polar –OH group linked t one end of the ring framework and a complex, nonpolar hydrocarbon chain at the other end.

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12
Q

Cholesterol

A

Cholesterol is also found in the membranes of most animal cells. The presence of cholesterol in plasma membranes has the same affect as double bonds. It disrupts the hydrophobic interactions in the fatty acid tails

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13
Q

Integral membrane protein

A

Integral or Trans-membrane proteins travel all the way across the membrane. They may cross once, twice or many times – depending on the protein being examined

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14
Q

Diffusion

A

The net movement of ions or molecules from a region of higher concentration to a region of lower concentration

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15
Q

Transmembrane protein

A

Transmembrane proteins have a number of important functions in the plasma membraneThey can aid transport of ions and polar molecules or they can help communicate signals from one side to the other

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16
Q

Peripheral membrane protein

A

Extrinsic or Peripheral membrane proteins are more loosely attached1 & 2 Partly embedded in the membrane
3 protein is anchored by a lipid

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17
Q

Cytoskeleton

A

The interconnected system of protein fibres and tubes that extends throughout the cytoplasm of a eukaryotic cell

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18
Q

Selectively permeable

A

Membranes that selectively allow, impede, or block the passage of atoms and molecules

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19
Q

Passive transport

A

The transport of substances across the cell membranes without expenditure of energy, as in diffusion.

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20
Q

Concentration gradient

A

The concentration difference that dives diffusion

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21
Q

Simple diffusion

A

Mechanism by which certain small substances diffuse through the lipid part of a biological membrane

22
Q

Channel protein

A

Transport protein that binds a specific single solute and transports it across the lipid bilayer

23
Q

Gated channel

A

Ion transporter in a membrane that switches between open, closed, or intermediate states.

24
Q

Carrier proteins

A

Transport protein that binds a specific single solute and transports it across the lipid bilayer

25
Q

Uniport

A

A uniporter is an integral membrane protein that is involved in facilitated diffusion. They can be either ion channels or carrier proteins. Uniporter carrier proteins work by binding to one molecule of substrate at a time and transporting it with its concentration gradient.

26
Q

Osmosis

A

The passive transport of water through a selectively permeable membrane in response to solute concentration gradients, a pressure gradient, or both.

27
Q

Aquaporin

A

A specialized protein channel that facilitates diffusion of water through cell membranes

28
Q

Hypotonic

A

Solution containing dissolved substances at a lower concentration than the cells it surrounds

29
Q

Hypertonic

A

Solution containing dissolved substances at higher concentrations than the cells it surrounds

30
Q

Isotonic

A

Equal concentration of water inside and outside cells

31
Q

Active transport

A

The mechanism by which ions and molecules move against the concentration gradient across a membrane, from the side with the lower concentration to the side with the higher concentration.

32
Q

Active transport pump

A

A pump which allows for active transport across the cell membrane

33
Q

Primary active transport

A

Transport in which the same protein that transports a substance also hydrolyzes ATP to power the transport directly

34
Q

Secondary active transport

A

Transport indirectly driven by ATP hydrolysis

35
Q

Proton/H+ pump

A

Pump that moves hydrogen ions across membranes and pushes hydrogen ions across the plasma membrane from the cytoplasm to the cell exterior.

36
Q

Calcium pump

A

Pump that pushes calcium from the cytoplasm to the cell exterior and from the cytosol into the vesicles

37
Q

Sodium-potassium pump

A

a pump which pushes 3 Na+ out of the cell and 2 K+ into the cell in the same pumping cycle.

38
Q

Membrane potential

A

An electrical voltage that measures the potential inside a cell membrane relative to the fluid just outside; it is negative under resting conditions and becomes positive during an action potential

39
Q

Electrochemical gradient

A

A difference in chemical concentration and electric potential across a membrane

40
Q

Symport

A

The transport of two molecules in the same direction across a membrane. Also referred to as cotransport.

41
Q

Cotransport

A

The transport of two molecules in the same direction across a membrane. Also referred to as Symport

42
Q

Exchange diffusion

A

A secondary active transport mechanism in which a molecule moves through a membrane channel into a cell and powers the transport of a second molecule out of a cell. Also referred to as antiport.

43
Q

Vesicle traffic

A

can move molecules between locations inside the cell, e.g., proteins from the rough endoplasmic reticulum to the Golgi apparatus. Membrane-bound and secreted proteins are made on ribosomes found in the rough endoplasmic reticulum.

44
Q

Endocytosis

A

In eukaryotes, the process in which molecules are brought into the cell from the exterior involving a bulging in of the plasma membrane that pinches off to form a endocytic vesicle.

45
Q

Bulk-phase endocytosis

A

Mechanism by which extracellular water is taken into a cell together with any molecules that happen to be in solution in the water. Also referred to as pinocytosis.

46
Q

Pinocytosis

A

Mechanism by which extracellular water is taken into a cell together with any molecules that happen to be in solution in the water. Also referred to a bulk-phase endocytosis.

47
Q

Receptor-medoated endocytosis

A

The selective uptake of macromolecules that bind to cell surface receptors concentrated in clathrin-coated pits.

48
Q

Coated pit

A

A depression in the plasma membrane that contains receptors for macromolecules to be taken up by endocytosis

49
Q

Clathrin

A

The network of proteins that coat and reinforce the cytoplasmic surface of cell membranes

50
Q

Phagocytosis

A

Process in which some types if cells engulf bacteria or other cellular debris to break them down

51
Q

Exocytosis

A

In eukaryotes, the process by which a secretory vesicle fuses with the plasma membrane and releases the vesicle contents to the exterior.