Chapter One - Basic Principles Flashcards

1
Q

What affect do enzyme inducers have?

A

Increase enzyme activity and decrease the drug concentration

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2
Q

What are the inducers?

A

PC BRAS
Phenytoin
Carbamazapine

Barbiturates
Rifampicin
Alcohol
Sulphonylureas

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3
Q

What affect do enzyme inhibitors have

A

Decrease enzyme activity and increase the drug concentration

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4
Q

What are the inhibitors?

A

AO DEVICES
Allopurinol
Omperprazole

Disulfiram
Erythromycin
Valproate
Isoniazid
Ciprofloxacillin
Ethanol - acute
Sulphonamides

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5
Q

Which drugs are stopped before surgery?

A

I LACK OP
Isulin
Lithium
Anticoags
COCP/HRT
K sparing diuertics
Oral hypoglycaemics
Perindopril and other ACEi

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6
Q

When do you stop COCP/HRT before surgery?

A

4 weeks

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7
Q

When do you stop lithium before surgery?

A

Day before

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8
Q

When do you stop K sparing diuertics and ACEi before surgery?

A

Day of surgery

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