Chapter 9 Nucleic Acids Flashcards

1
Q

Nucleotide?

A

Nitrogenous base
Pentose
Phosphate

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2
Q

Nucleoside

A

Nitrogenous base

Pentose

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3
Q

Nucleobase?

A

Nitrogeneous base

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4
Q

What is the general structure of nucleotides?

A

A phosphate group attached onto a 5 carbon sugar by a phosphoester bond and a purine or pyramidine attached on with a glycosidic bond

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5
Q

How do we link two nucleotides together?

A

The hydroxyl attaches onto phosphate group and we have a phospho diester linkage

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6
Q

How are DNA sequences written?

A

5’ to 3’

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7
Q

What are oligonucleotides?

A

Less than 50 nucleotides in length

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8
Q

What are DNA AND RNA sensitive to?

A

Alkaline hydrolysis

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9
Q

What were the names of the three experiments?

A

The transforming principle
The avery McLeod McCarty
The Hershey and chase

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10
Q

What did the transforming principle conclude?

A

The storage of genetic material

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11
Q

What did the Avery McLeod conclude?

A

The transforming factor is nucleic acids

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12
Q

What did Hershey and chase conclude?

A

That NA were responsible for the storage and transfer of genetic material

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13
Q

What is chargaffs rule

A

A+C= T+G

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14
Q

What is the length of space between the base pairs

A

3A

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15
Q

Is the double helix right handed or left?

A

Right

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16
Q

What points outside and what points inside?

A

Phosphate groups are outside

Bases inside

17
Q

What is the width of the double helix?

A

20A

18
Q

What is the pitch of the helix (one turn)

A

36A or 10.4 nucleotides

19
Q

What is present on RNA but not DNA?

A

A hydroxyl group no O atom at C2

20
Q

Is DNA uni or bi directional

A

Bi directional