Chapter 9 - Exam 2

Question 1

Luteal phase

Answer 1

1. Luteinziation (formation of CL)
2. Synthesis +secretion of large amounts of P4
3. Luteolysis

Question 2

Lutenization

Answer 2

CL originates from ovulatory follicle, granulosa cells ➡️ large luteal cell, theca interna ➡️ small luteal cell

Question 3

Functionality CL/P4 production

Answer 3

Number of luteal cells, vascularization = blood flow delivery of precursors , recipes basal/tonic LH ➡️theca cells ➡️ cholesterol

Question 4

P4 targets

Answer 4

Hypothalamus- reduce GNRH pulses, uterus - uterine quiescence plus’s quiet, mammary glands - protes development

Question 5

P4 effects

Answer 5

1. Negative feedback
2. Inhibits uterine contractions and reduces Mayomedeial tone
3. Promotes production of uterine milk + other secretion
4. Completely inhibits estrus or heat
5. Prevents LH- surge
6. Primes/prepares hypothalamus to be more sensitive to E2
7. Promotes alveolar (milk production) development in mammary gland s

Question 6

Luteolysis effects

Answer 6

Stops P4 production, structural regression to kill CL, removes negative feed back to hypothalamus

Question 7

What is in the structural regression

Answer 7

Apoptosis (programmed cell death), necrosis - death due to pathological damage ( phagocytic cell, lymph acytes secrete cytokines ➡️ activate macrophages, interferons, tumor necrosis factors

Question 8

Functionally of CL

Answer 8

Number of luteal cell, vascularization (increase blood flow)

Question 9

P4 synthesis

Answer 9

Requires basal/tonic LH, theca cells stimulate GnRH