chapter 4 - Exam 2 Flashcards
Endocrine is
Slower, last longer, from brain
Neural is
Faster, short lived, from brain
Half life
Time required for one-half of a hormone to disappear from blood or tissues,
What is half life determined by
Mythel group
List half-times of, LH, FSH, GnRH, eCG
LH : 20-30 min
FSH : 3-4 hours
GnRH : 7 min
eCG : 3-4 days
Hormone Potency
How long to get to desired effect
What is the hormone potency effected by
Receptor density, hormone receptor affinity, hormone concentration, half-life
Receptor density
More vs less binding site
Hormone receptor affinity
Performance, preferential binding
Hormone concentration
More available molecules increases binging rates
Half-life
Longer half-life greater biological activity
Positive and negative feedback
All repro functions are regulated by this
Negative
Suppresses step prior or before
Positive
Promotes prior step to encourage more production
Tissues origins
Hypothalamus, nureopeptides, pituitary, gomadal, uterine, placental
Mode of actin classifications
Nurerohormones, releasing hormones, gonadotropins, pregnancy maintenance, luteolytic hormones.
Biochemical classifications
Peptides, glycoproteins, steroids, prostaglandins
What are steroids made of
Cholesterol
What do neurohormones do
Connection between endocrine and nerves
What do releasing hormones do
Causes release of another hormones
What do gonadotropins do
Effect gonads
What I sexual promoters do
Promotes sexual behavior
What do pregnancy maintenance do
Maintains pregnancy
What do luteolytic hormones do
Kills CL
Peptides
Degraded in liver and kidneys
Glycoproteins
Metabolized in liver and kidneys
Steroids
Metabolized in liver and lungs
Prostaglandeins
Rapidly degraded in blood circulation and lungs
Analogs
similar structure to hormones, bind to specific receptors, cause same reaction as native hormones
Agonists
Promote greater physiological activity, greater affinity receptor
Antagonist
Have greater affinity for receptors, weaker biological activity
