Chapter 9 Endocrinology Toronto Notes Flashcards
Hashimoto’s Thyroiditis
Common or Uncommon?
T notes 2017
most common form of primary hypothyroidism in North America
Hashimoto’s Thyroiditis
VITAMIN CDEF
T notes 2017
chronic autoimmune thyroiditis characterized by both cellular and humoral factors in the
destruction of thyroid tissue
Hashimoto’s Thyroiditis
Two major forms
T notes 2017
two major forms: goitrous and atrophic; both forms share same pathophysiology but differ in
the extent of lymphocytic infiltration, fibrosis, and thyroid follicular cell hyperplasia
Hashimoto’s Thyroiditis
-goitrous variant
T notes 2017
-goitrous variant usually presents with a rubbery goitre and euthyroidism, then hypothyroidism
becomes evident
-associated with fibrosis
Hashimoto’s Thyroiditis
• atrophic variant
T notes 2017
• atrophic variant patients are hypothyroid from the start
-associated with thyroid lymphoma
Hashimoto’s Thyroiditis
goitrous vs atrophic variant
Which is rubbery?
T notes 2017
goitrous
Hashimoto’s Thyroiditis
goitrous vs atrophic variant
which one associated with fibrosis
T notes 2017
goitrous
Hashimoto’s Thyroiditis
goitrous vs atrophic variant
which one has the clinical picture of euthyroidism, then hypothyroidism
T notes 2017
goitrous
Hashimoto’s Thyroiditis
goitrous vs atrophic variant
which has the clinical picture of hypothyroidism from the start?
T notes 2017
atrophic
Hashimoto’s Thyroiditis
goitrous vs atrophic variant
which associated with thyroid lymphoma?
T notes 2017
atrophic
