Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

British National Formulary > Chapter 9- Blood & Nutrition > Flashcards

Chapter 9- Blood & Nutrition Flashcards

1
Q

Why do they use hydroxycarbamide in sickle cell disease

A

It can reduce the frequency of crises and the need for blood transfusions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which gender is G6PD deficiency most common in?

A

Males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What ethnicity is G6PD deficiency most common in

A

African
Asian
Oceania
Southern Europe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Patients with G6PD deficiency are susceptible to what when they take certain drugs

A

Acute haemolytic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

True or false: darbepoetin has a longer half life than epoetin therefore can be administered more frequently

A

False - less frequently

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Haemoglobin target

A

10-12g/100ml

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

True or false: ascorbic acid can increase the absorption of iron

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

There have been reports of what with IV iron

A

Serious hypersensitivity reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Iron PO can cause what side effects

A 
Constipation that can lead to faecal impaction 
Diarrhoea 
Epigastric pain 
GI 
Nausea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

When the haemoglobin is in range- treatment with iron should continue for how long

A

3 months to replenish the iron stores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most megaloblastic anaemias result from a lack of either of what two things

A

Vitamin B12

Folate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What do you give if someone has megaloblastic anaemia due to vitamin B12 deficiency

A

Hydroxocobalamin every 3 months (which has replaced cyanocobalamon due to its longer half life)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

For folate deficient megaloblastic anaemia what is given?

A

Daily folic acid for 4 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Other that folic acid, what is good in folate deficient megaloblastic anaemia

A

Folinic acid (calcium folinate) but generally used in association with cytotoxic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Caution with folic acid?

A

Never give alone for pernicious anaemia (may precipitate subacute combined degeneration of the spinal cord)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Folic acid can be sold to the public providing the dose does not exceed what?

A

500mcg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Name three iron chelators used in iron overload

A

Deferasirox
Deferiprone
Desferrioxamine

18
Q

MHRA advice with calcium gluconate 10%

A

Give the plastic version not glass in patients under 18 and those with renal impairment due to risk of aluminium accumulation

19
Q

Why does magnesium cause laxative effects

A

It’s not well absorbed in the GI tract

20
Q

What’s used for the management of magnesium toxicity

A

Calcium gluconate

21
Q

If someone has acute porphyria and require a treatment contraindicated but there is no alternative and it’s a life threatening condition - what should be monitored?

A

Urinary porphobilinogen excretion

22
Q

What can be administered for haem replacement in moderate, severe or unremitting acute porphyria crises

A

Haem arginate by short IV infusion

23
Q

What prevents the absorption of copper in Wilson’s disease

A

Zinc acetate

Trientine dihydrochloride

24
Q

What lowers plasma zinc concentration

A

Hypoproteinaemia

25
Q

Deficiency of vitamin A is associated with what

A

Ocular defects and increased susceptibility to infections

26
Q

Vitamin C (ascorbic acid) therapy is essential in what?

A

Scurvyyyy

27
Q

Why might patients with fat malabsorption especially in biliary obstruction or hepatic disease become deficient in vitamin K

A

Because vitamin K is a fat soluble vitamin

28
Q

What is given to prevent neural tube defects in pregnancy

A

Folic acid

29
Q

Another name for vitamin A and why is it needed

A

Retinol

Helps night vision

30
Q

Sources of vitamin A

A

Eggs
Butter
Fish oils

31
Q

Name for vitamin B 1

A

Thiamine

32
Q

What vitamin is riboflavin

A

Vitamin B 2

33
Q

What is vitamin B6

A

Pyridoxine

34
Q

What is vitamin B 12

A

Cyanocobalamin

35
Q

Signs of vitamin C deficiency

A

Gingival bleeding
Scurvy
Bleeding margins
Petechia of skin

36
Q

Vitamin D2

A

Ergocalciferol

37
Q

Vitamin D3

A

Cholecalciferol

38
Q

Another name for vitamin E

A

Tocopherol

39
Q

Another name for vitamin K and what’s the water soluble version

A

Menapthone

Menadiol

40
Q

Why is vitamin K given to newborns

A

Prevent haemorrhagic disease

British National Formulary (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions