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PSA > Chapter 9 > Flashcards

Chapter 9 Flashcards

1
Q

Who are more likely to experience haemorrhage on heparin?

A

Renal failure

<50kg

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2
Q

What must you prescribe initially with warfarin
why?
until when?

A

Heparin
Because of its initial procoagulant effect
INR>2

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3
Q

Side effects: Aspirin (3)

A

Haemorrhage
Peptic ulcers
Tinnitus in large doses

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4
Q

Side effects: Digoxin (8)

A

Nausea, vomiting + diarrhoea
Confusion + drowsiness
Blurred vision, visual halos, xanthopsia

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5
Q

What levels of potassium alter the effect of digoxin?

A

Hypokalaemia augments its effects

Hyperkalaemia limits digoxin’s effects

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6
Q

Side effects: Amiodarone (9)

A
  1. Pulm. fibrosis
  2. Corneal deposits
  3. Skin greying
  4. Hyper/hypothyroidism
  5. Liver fibrosis/hepatitis
  6. Arrhythmias
  7. Photosensitivity
  8. Thrombophlebitis
  9. Peripheral neuropathy
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7
Q

Side effects: Lithium
Early
Intermediate
Late (5)

A

Early - tremor
Intermediate - tiredness
Late - arrhythmias, diabetes insipidus, renal failure, coma, seizures

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8
Q

Side effects: Haloperidol (2)

A

Dyskinesias

Drowsiness

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9
Q

Side effects: Statins (4)

A

Myalgia
Rhabdomyolysis
Raised transaminases
Abdominal pain

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10
Q

Side effects: Fludrocortisone

A

Sodium/water retention

Hypertension

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11
Q

Which drugs have potent interactions with alcohol? (9)

A 
Metformin 
NSAIDs
MAOinhibs
Barbiturates
Opioids
Benzos
Warfarin
Methotrexate
Disulfiram
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12
Q

Effect of alcohol with: Metformin

A

Lactic acidosis

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13
Q

Effect of alcohol with: NSAIDs

A

GI bleeding

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14
Q

Effect of alcohol with: MAOinhibs

A

Hypertensive crisis

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15
Q

Effect of alcohol with: Opioids, barbiturates and benzos

A

Sedation

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16
Q

Effect of alcohol with: Warfarin

A

Increased anticoagulation with acute alcohol

Decreased anticoagulation with chronic alcohol

17
Q

Effect of alcohol with: Metronidazole, disulfiram

A

Sweating, flushing, N+V

18
Q

Side effects: Beta blockers (6)

A 
Wheeze in asthmatics
Worsening of acute HF
Cold peripheries
Fatigue
Bradycardia
Hypotension
19
Q

Side effects: Sodium Valproate (3)

A

Teratogenicity, tremor, tubby

20
Q

Side effects: Carbamazepine

A 
Hyponatraemia (SIADH)
Rash
Dysarthria
Ataxia
Nystagmus
21
Q

Side effects: Lamotrigine

A

Rash

Stevens Johnson syndrome

PSA (9 decks)

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