Chapter 9 Flashcards
Coordinates and directs the activity pf the body’s cells
Endocrine and Nervous system
“built for speed”
Nervous system
The major processes Endocrine control are
Reproduction Growth and development Mobilizing body defenses against stress Maintaining electrolytes, water and nutrient balance of the blood Regulating cellular metabolism Energy balance
Scientific study of hormones and endocrine organs is called
Endocrinology
Although many different hormones are produced, nearly all of them can be classified chemically as either
amino acid based molecules or steroids
Steroid hormones are made from
cholestrol
Gonads
ovaries and testes
Steroid hormones include
sex hormones made by gonads and the hormones produced by the adrenal cortex
Local hormones
Prostaglandins
Prostaglandins are made from
highly active lipids released from nearly all cell membranes.
A given hormone affects only certain tissue cells or organs, referred to as its
target cell or target organs
Hormone comes from the Greek word meaning
to arouse
Only 2 mechanisms by which hormones trigger changes in cells
Steroidal hormones
Thyroid Hormones
Water soluble, non-steroidal hormones, which are unable to enter the target cells
Protein and peptide hormones
Protein and peptide hormones, what do they?
They bind to hormone receptors situated on the target cell’s plasma membrane and utilize a second messenger system
Ceif means of regulating blood levels of nearly all hormones
Negative feedback mechanism
The stimuli that activate the endocrine organs fall into 3 major categories
Hormonal
Humoral
Neural
Most common stimulus is a
Hormonal stimulus, in which endocrine organs are prodded into action by other hormones
Changing blood levels of certain ions and nutrients may also stimulate hormone release, such stimuli are also referred to as
Humoral stimuli
Bloodborne chemicals
Hormonal stimuli
The word humor indicates
various body fluids
In isolated cases, nerve fibers stimulate hormone release and the the target cells are said to respond to
neural stimuli
Ex of Neural stimuli
sympathetic nervous system stimulation of the adrenal medulla to release norepinephrine and epinephrine during periods of stress
Major endocrine organs
pituitary thyroid parathyroid adrenal pineal glands gonads
Part of NS, major Endocrine organ, produces several organs
Hypothalamus
Function of hormone producing glands is purely
endocrine
Function of non hormone producing glands is
mixed- both endocrine and exocrine
Endocrine glands are
ductless glands, that produce hormones that they release into the blood or lymph
Endocrine glands have a
rich blood supply
Exocrine glands release their products at
the body’s surface or into body cavities through cavitie
Pituitary glans is surrounded by what?
“Turk’s saddle” of the sphenoid bone
2 functional lobes or pituitary glands
anterior pituitary (glandular tissue) posterior pituitary (nervous tissue)
Growth hormone and prolactin exert their major roles on
nonendocrine targets
thyrotropic, adrenocorticotropic and the 2 gonadotropic hormones are all
tropic hormones
all anterior pituitary hormones
- are proteins or peptides
- act through 2nd membrane systems
- are regulated by hormonal stimuli and in most cases negative feedback
General metabolic hormone
Growth hormone GH
GH’s major effects are directed to the growth of
skeletal muscles and long bones of the body, which determines the final body size
if untreated, both deficits and excess of GH, may result in
structural abnormalities
Hyposecreation of GH during childhood leads to
pituitary dwarfism
Hypersecreation during childhood leads to
gigantism
If hypersecretion occurs after long bone growth has ended,
acromegaly results
Thickening of soft tissues leads to
coarse or malformed facial features
Most cases of hypersecreation ny endocrine organs (pituitary and the other endocrine organs) result from
tumors of the affected gland
Protein hormone structurally similar to growth hormone
Prolactin PRL
target of prolactin
breast
After birth what does prolactin do?
Stimulates and maintains milk production by the mother’s breasts
Regulates the endrocrine activity of the cortex portion of the adrenal gland
Adrenocorticotropic hormone ACTH
Influences the growth and activity of the thyroid gland
Thyroid stimulating hormone (TSH)
Thyroid stimulating hormone (TSH) is also called
Thyrotropic hormone (TH)
Regulate the hormonal activity of the gonads
Gonadotropic
In women, what stimulates follicle development in the ovaries
the gonadotropin follicle-stimulating hormones FSH
As the FSH mature, they produce
estrogen and eggs are readied for ovulation
in men, FHS stimulates sperm development by the
testes
Triggers ovulation of an egg from the ovary and causes the ruptured follicle to produce progesterone and some estrogen
Luteinizing hormone LH
in men LH stimulates
testosterone production by the interstitial cells of the testes
Hyposecreation of FSH or LH leads to
sterility in both male and females
Tropic hormone
stimulate certain endocrine organs to secret their hormones
Anterior pituitary gland controls
“master endocrine gland”
releasing or inhibiting hormones are produced by
inhibiting hormones
hypothalamus makes 2 additional hormones
oxytocin and antidiuretic hormone
oxytocin and antidiuretic hormone are transported along the axons of the
hypothalamic neurosecretory cells
posterior pituitary is not an endocrine gland because
it does not make the peptide hormones it releases
posterior pituitary acts as a
storage area for hormones made by hypothalamic neurons