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Katzung Trevor Pharm > Chapter 9 > Flashcards

Chapter 9 Flashcards

1
Q

What two reuptake transporters are inhibited by cocaine and tricyclics?

A

NET and DAT

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2
Q

What two enzymes are amphetamines resistant to?

A

MAO and COMT

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3
Q

Why do α2 agonists work in the treatment of glaucoma?

A

decrease production of aqueous humor

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4
Q

What do β3 receptors do in fat cells?

A

increase lipolysis

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5
Q

What effect do α2 agonists produce when administered intravenously?

A

vasoconstriction

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6
Q

Which agonists increase insulin secretion?

A

β2

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7
Q

What α2 agonists are used in the Tx of glaucoma?

A

Apraclonidine

Brimonidine

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8
Q

What is the MOA of midodrine?

A

α1 agonist

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9
Q

What is a common side effect of β2 agonists in the skeletal muscle?

A

tremor

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10
Q

What is a common side effect after heart transplant regarding autonomic effect?

A

lack of sympathetic tone to heart for two years

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11
Q

Would a pheochromocytoma present with increased or decreased blood volume?

A

decreased

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Katzung Trevor Pharm (16 decks)

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