chapter 9 Flashcards

1
Q

Rosalind Franklin founded

A

x ray diffraction pattern of dna; this helped find the double helix structure

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2
Q

what three things are each nucleotide made of?

A

phosphate, sugar and a base

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3
Q

what kind of nucleotides are DNA and RNA

A

polynucleotides

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4
Q

difference between ribose and deoxyribose

A

different element at 2’, H in deoxyribose and OH at ribose

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5
Q

what is dna made of

A

two polynucleotide joined together by two hydrogen bases, twisted into helical shape

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6
Q

where is the sugar phosphate bone

A

on the outside

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7
Q

where are the nitrogenous bases (pair)

A

they are perpendicular to each other in the interior

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8
Q

what forms when A pairs with T

A

two hydrogen bonds

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9
Q

what forms when G pairs with C

A

three hydrogen bond

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10
Q

where is DNA found in

Eukaryotes:

Prokaryotes:

A

Eukaryotes: Nucleus

Prokaryotes: Nucleoid (cytoplasm)

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11
Q

What happens in cell replication? (how does it work)

A

DNA is broken into two, forms / pairs with a new strand

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12
Q

What direction does DNA replication happen in?

A

5’->3’

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13
Q

replication is continuous on

A

3’->5’

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14
Q

replication is discontinuous (forms short segments) on

A

5’->3’

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15
Q

dna replication begins at _____ and ____ to produce a bubble

A

the origin; unwinds

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16
Q

helicase ___ the helix

17
Q

where is the nucleotides add to the growing chain? (dna polymerase)

A

end of 3’; can only be added where there is an OH

18
Q

backbone is sealed by

A

DNA Ligase

19
Q

DNA is transcribed to

20
Q

RNA is transcribed to

21
Q

how is the phenotype determined

A

presences and action of protein

22
Q

sequence of dna provides

A

code for constructing protein

23
Q

Transcription means

A

to rewrite the DNA code to RNA using its “language”

24
Q

words in the translation are called

25
RNA to protein "language" is
Nucleotide "language" to amino acid "language"
26
codon
three nucleotides specify one amino acid
27
redundant
more than one codon can make this amino acid
28
ambiguous
codon made for one amino acid that does not code with others
29
Stages of transcription: Initiation- Elongation- Termination-
Initiation- RNA polymerase binds to a promoter while helix unfolds Elongation- RNA added to the chain (tracks DNA template in 5'->3' ; unwinds and rewinds DNA as it is read) Termination-RNA polymerase reaches a terminator sequences and detaches from template
30
introns
eukaryotic mRNA
31
exons
separates coding regions
32
mutation
change in nucleotide sequence
33
spontaneous mutation
happens because on an error in dna replication of recombination
34
RNA splicing
removing of introns to join exons together producing continuous coding sequences
35
rRNA
ribose RNA
36
mRNA
messenger RNA
37
tRNA
transport RNA