Chapter 8 Viruses And Virology Flashcards

1
Q

Capsid

A

Protein shell that surrounds the genome of a virus particle

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2
Q

Capsomere

A

The subunit of a capsid

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3
Q

Concatemer

A

Two or more linear nucleic acid molecules joined covalently in tandem

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4
Q

Early protein

A

A protein synthesized soon after virus infection and before replication of the virus genome

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5
Q

Enveloped

A

In reference to a virus, having a lipoprotein membrane surrounding the virion

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6
Q

Host cell

A

A cell inside which a virus replicates

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7
Q

Late protein

A

A protein, typically a structural protein, synthesized late in virus infection

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8
Q

Lysogen

A

A bacterium containing a prophase

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9
Q

Lysogeny

A

A state in which the viral genome is replicated in step with the genome of the host

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10
Q

Lytic pathway

A

The type of virus infection that leads to virus replication and destruction of the host cell

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11
Q

Bacteriophage

A

A virus that infects bacterial cells

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12
Q

Middle protein

A

Protein with either a structural or catalytic function synthesized after the early proteins in a virus infection

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13
Q

Nucleocapsid

A

The complex of nucleic acid and proteins of a virus

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14
Q

Overlapping genes

A

Two or more genes in which part or all of one gene is embedded in the other

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15
Q

Plaque

A

A zone of lysis or growth inhibition caused by virus infection of a lawn of sensitive host cells

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16
Q

Prophage

A

The lysogenic form of a bacteriophage

17
Q

Provirus

A

The genome of a temperate or latent animal virus when it is replicating in step with the host chromosome

18
Q

Replicative form

A

A double-stranded DNA molecule that is an intermediate in the replication of viruses with single-stranded DNA genomes

19
Q

Retrovirus

A

A virus whose RNA genome is replicated via a DNA intermediate

20
Q

Reverse transcriptase

A

The retroviral enzyme that can produce DNA from an RNA template

21
Q

RNA replicase

A

An enzyme that can produce RNA from an RNA template

22
Q

Rolling circle replication

A

A DNA replication mechanism in which one strand is nicked and unrolled for use as a template to synthesize a complementary strand

23
Q

Temperate virus

A

A virus whose genome can replicate along with that of its host without causing cell death, in a state called lysogeny (bacterial viruses) or latency (animal viruses)

24
Q

Titer

A

The number of infections virions in a viral suspension

25
Q

Virion

A

The infectious virus particle, the viral genome surrounded by a protein coat and sometimes other layers

26
Q

Virulent virus

A

A virus that lyses or kills the host cell after infection

27
Q

Virus

A

A genetic element containing either RNA or DNA surrounded by a protein capsid and that replicates only inside host cells

28
Q

How does a virus differ from a cell?

A

Shape (typically smaller), genome length and the amount of genes encoded based on RNA or DNA usage, cannot replicate on its own and needs a virion to survive outside host cell

29
Q

Why does a virus need a host cell?

A

Because it relies on the host cell’s energy for energy, metabolic intermediates, protein synthesis