Chapter 8 - Treatments for Bipolar Disorders Flashcards
Treatments for Bipolar Disorders include:
lithium and mood stabilizing drugs/anti-bipolar drugs, and atypical antipsychotics drugs that specifically help treat MANIC episodes
What is lithium?
A metallic element that occurs in nature as a mineral salt. Effective for reducing bipolar symptoms, discovered by John Cade
Mood stabilizers as prophylactic drugs?
Prophylactic drugs help prevent symptoms from developing, must continue drugs or high chance of relapsing
True or false these drugs also help depressive episodes?
True but to a lesser extent than they manic episodes
How do therapists treat bipolar disorder?
Combination of both mood stabilizers and antidepressant drugs
True or false some antidepressants can cause manic episodes in some patients?
True
First theory about why mood stabilizers help bipolar disorder?
Suggest that the drugs change synaptic activity in neurons
What are second messengers?
Chemical changes within a neuron just after the neuron receives a neurotransmitter message and just before it responds, relay the original message from the receipt site to the firing mechanism of the neutron
Who are the first messengers?
Neurotransmitters
Mood stabilizers affect which messengers?
A neurons’ second messenger
Antidepressants affect which messengers?
A neurons’ first messenger
Second theory about why mood stabilizers help bipolar disorder?
Lithium and other mood stabilizing drugs increase the production of a protein called brain-derived neurotrophic factor (BDNF) and other proteins within certain neurons whose job is to prevent cell death. Therefore, increasing the health and functioning of those cells
Third theory about why mood stabilizers help bipolar disorder?
Lithium and other mood stabilizing drugs improve the functioning of or communications between key structures in the brain
Lithium’s link to brain structures?
Lithium increases the size of the hippocampus and the amount of gray matter in bipolar patients
What is Adjunctive psychotherapy?
Individual, group, or family therapy as an adjunct to mood stabilizing drugs